内镜球囊扩张治疗原发性阻塞性巨静脉炎:中心经验

Sofia Morão, Vanda Pratas Vital, Dinorah Cardoso, Fátima Alves, F. C. Mota, J. Pascoal
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摘要

简介:先天性梗阻性血压计可以用内镜下球囊扩张术治疗,特别是一岁以下的儿童。我们报告的是六年的经验。患者和方法:2009 - 2014年(6年)所有经内镜球囊扩张治疗原发性梗阻性计量器(POM)的患者。POM的诊断是基于输尿管远端扩张大于7mm, MAG - 3利尿肾图梗阻性曲线和无膀胱输尿管反流(VUR)。诊断后,所有患者均采用抗生素预防治疗。手术指征是结合临床、超声和肾造影结果。全麻下逆行输尿管造影后,在直视和透视下对输尿管膀胱连接处进行高压球囊扩张,直至狭窄环消失。放置双j型导管。随访采用超声及利尿肾图。干预的成功以HUN的改善(至少2个等级)来定义。结果:共有9例患者接受了单输尿管手术,2例女孩,7例男孩,平均年龄7岁。干预后6个月(范围1-14)。五个是左边的,四个是右边的。所有患者产前诊断为输尿管积水(HUN)。无患者失访(平均46.7个月)。所有患者的HUN均大于3级,术前MAG3利尿肾图均为梗阻性。受影响肾脏的平均差功能为46.2%(范围40-53%)。手术治疗的主要指征是进展性HUN。所有患者均行内镜治疗,无术中并发症。超声显示6例(66.7%)患者HUN改善。3例患者再植(33.3%)。术后平均差肾功能(DRF)为47.4%(范围41-53%)。在最近的随访评估中,所有患者仍无症状。讨论:内镜下球囊扩张术是治疗需要手术干预的POM的一种有效选择,可以考虑在儿童中进行一线治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dilatação Endoscópica de Balão para Tratamento de Megaureter Obstrutivo Primário: Experiência de um Centro
Introduction: Congenital obstructive megaureter may be treated with endoscopic balloon dilatation, particularly in children under one year of age. We report our experience over a six year period. Patients and methods: All patients with diagnosis of primary obstructive megaureter (POM) treated with endoscopic balloon dilatation from 2009 to 2014 (6 years) were included. The diagnosis of POM was based on dilatation of the distal ureter greater than 7 mm, obstructive curve on MAG 3 diuretic renogram and absence of vesicoureteral reflux (VUR). After diagnosis, conservative management was maintained with antibiotic prophylaxis in all patients. The indications for surgery were a combination of clinical, ultrasonographic and renographic findings. Under general anesthesia and after retrograde ureteropielography, high pressure balloon dilation of the ureterovesical junction was performed under direct and fluoroscopic vision until the disappearance of the narrowed ring. A double-J catheter was positioned. Follow-up was performed with ultrasonography and diuretic renogram. The success of the intervention was defined by improvement of HUN (at least 2 grades). Results: A total of nine patients underwent this procedure on a single ureter, two girls and seven boys, with a mean age of 7. 6 months (range 1-14) at the intervention. Five were left sided and four were right sided. All patients had prenatal diagnosis of hydroureteronephrosis (HUN). No patients were lost to follow-up (average 46.7 months). They all had HUN greater than grade 3 and preoperative MAG3 diuretic renogram was obstructive in all cases.  Mean differential function of the affected kidney was 46.2% (range 40-53%). The main indication for surgical treatment was progressive HUN. All patients were treated endoscopically with no intraoperative complications. Ultrasound showed improvement of the HUN in six patients (66.7%). Three patients were reimplanted (33.3%). The mean differential renal function (DRF) after the procedure was 47.4% (range 41-53%). At the latest follow-up assessment, all patients remained asymptomatic. Discussion: Endoscopic balloon dilatation is a useful option in the management of POM requiring surgical intervention and may be considered first line treatment in small children.
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