{"title":"长春花内生放线菌体外抗氧化活性和体内α -葡萄糖苷酶活性的研究g .不","authors":"D. Jacintha Jasmine, P. Agastian","doi":"10.1016/j.jopr.2013.06.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Aim</h3><p>Antioxidant compounds in food play an important role as a health protecting factor. Scientific evidence suggests that antioxidants reduce the risk for chronic diseases including cancer and heart disease. The present study was to evaluate the free radical scavenging activity and alpha glucosidase activity of Ethyl acetate extracts of endophytic actinomycetes (EEA) isolated from the roots of <em>Catharanthus roseus</em> (l.) G. Don.</p></div><div><h3>Method</h3><p>The EEA was screened for its capability in lowering blood sugar level and radical scavenging activity against Hydroxyl (HO<sup>-</sup>), Hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), Nitric oxide (NO) and scavenging of stable radical 2,2-diphenyl-1-picrylhydrazyl or DPPH and using standard procedures.</p></div><div><h3>Result</h3><p>Significant free radical scavenging activity and marked alpha glucosidase activity were exhibited by EEA isolated from the roots of <em>Catharanthus roseus</em> (l.) G. Don.</p></div><div><h3>Conclusion</h3><p>The extract used in the study possesses significant antioxidant activity as well as an alpha glucosidase inhibition and have the potential for application in pharmaceuticals.</p></div>","PeriodicalId":16787,"journal":{"name":"Journal of Pharmacy Research","volume":"6 6","pages":"Pages 674-678"},"PeriodicalIF":0.0000,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jopr.2013.06.007","citationCount":"14","resultStr":"{\"title\":\"In vitro antioxidant activity and in vivo alpha glucosidase activity of endophytic actinomycetes isolated from Catharanthus roseus (l.) G. Don\",\"authors\":\"D. Jacintha Jasmine, P. Agastian\",\"doi\":\"10.1016/j.jopr.2013.06.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Aim</h3><p>Antioxidant compounds in food play an important role as a health protecting factor. Scientific evidence suggests that antioxidants reduce the risk for chronic diseases including cancer and heart disease. The present study was to evaluate the free radical scavenging activity and alpha glucosidase activity of Ethyl acetate extracts of endophytic actinomycetes (EEA) isolated from the roots of <em>Catharanthus roseus</em> (l.) G. Don.</p></div><div><h3>Method</h3><p>The EEA was screened for its capability in lowering blood sugar level and radical scavenging activity against Hydroxyl (HO<sup>-</sup>), Hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), Nitric oxide (NO) and scavenging of stable radical 2,2-diphenyl-1-picrylhydrazyl or DPPH and using standard procedures.</p></div><div><h3>Result</h3><p>Significant free radical scavenging activity and marked alpha glucosidase activity were exhibited by EEA isolated from the roots of <em>Catharanthus roseus</em> (l.) G. Don.</p></div><div><h3>Conclusion</h3><p>The extract used in the study possesses significant antioxidant activity as well as an alpha glucosidase inhibition and have the potential for application in pharmaceuticals.</p></div>\",\"PeriodicalId\":16787,\"journal\":{\"name\":\"Journal of Pharmacy Research\",\"volume\":\"6 6\",\"pages\":\"Pages 674-678\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.jopr.2013.06.007\",\"citationCount\":\"14\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pharmacy Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0974694313002429\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmacy Research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0974694313002429","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
In vitro antioxidant activity and in vivo alpha glucosidase activity of endophytic actinomycetes isolated from Catharanthus roseus (l.) G. Don
Aim
Antioxidant compounds in food play an important role as a health protecting factor. Scientific evidence suggests that antioxidants reduce the risk for chronic diseases including cancer and heart disease. The present study was to evaluate the free radical scavenging activity and alpha glucosidase activity of Ethyl acetate extracts of endophytic actinomycetes (EEA) isolated from the roots of Catharanthus roseus (l.) G. Don.
Method
The EEA was screened for its capability in lowering blood sugar level and radical scavenging activity against Hydroxyl (HO-), Hydrogen peroxide (H2O2), Nitric oxide (NO) and scavenging of stable radical 2,2-diphenyl-1-picrylhydrazyl or DPPH and using standard procedures.
Result
Significant free radical scavenging activity and marked alpha glucosidase activity were exhibited by EEA isolated from the roots of Catharanthus roseus (l.) G. Don.
Conclusion
The extract used in the study possesses significant antioxidant activity as well as an alpha glucosidase inhibition and have the potential for application in pharmaceuticals.
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