{"title":"癌症光动力治疗中可活化光敏剂的研制","authors":"Hiroaki Horiuchi","doi":"10.2530/jslsm.jslsm-41_0033","DOIUrl":null,"url":null,"abstract":"Photodynamic therapy is expected to be a minimally invasive treatment for cancer. Activatable photosensitizers have attracted considerable attention as one of the strategies for improving the minimally invasive properties. The activatable photosensitizer is in the photo-inactive (OFF) state in normal tissues; however, it is in the photoactive (ON) state in the tumor tissue. In this review, low pH- and sono-activatable photosensitizers are introduced.","PeriodicalId":19350,"journal":{"name":"Nippon Laser Igakkaishi","volume":"329 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development of Activatable Photosensitizer for Photodynamic Therapy of Cancer\",\"authors\":\"Hiroaki Horiuchi\",\"doi\":\"10.2530/jslsm.jslsm-41_0033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Photodynamic therapy is expected to be a minimally invasive treatment for cancer. Activatable photosensitizers have attracted considerable attention as one of the strategies for improving the minimally invasive properties. The activatable photosensitizer is in the photo-inactive (OFF) state in normal tissues; however, it is in the photoactive (ON) state in the tumor tissue. In this review, low pH- and sono-activatable photosensitizers are introduced.\",\"PeriodicalId\":19350,\"journal\":{\"name\":\"Nippon Laser Igakkaishi\",\"volume\":\"329 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nippon Laser Igakkaishi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2530/jslsm.jslsm-41_0033\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nippon Laser Igakkaishi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2530/jslsm.jslsm-41_0033","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Development of Activatable Photosensitizer for Photodynamic Therapy of Cancer
Photodynamic therapy is expected to be a minimally invasive treatment for cancer. Activatable photosensitizers have attracted considerable attention as one of the strategies for improving the minimally invasive properties. The activatable photosensitizer is in the photo-inactive (OFF) state in normal tissues; however, it is in the photoactive (ON) state in the tumor tissue. In this review, low pH- and sono-activatable photosensitizers are introduced.
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