CERVICAL CANCER INCIDENCE AND MORTALITY IN ALMATY IN 2005-2022

Relevance: In Kazakhstan, the standardized incidence rate of cervical cancer for 2022 was 19 per 100,000 women, and the mortality rate was 5.9 per 100,000 female population. The overall survival of cervical cancer in the Republic of Kazakhstan for 2022 was 59.6% (95% CI: 50.7-54.2). Since 2008, in Kazakhstan, there has been a National Screening Program for cervical cancer for women from 30 to 70 years old with an interval of 4 years. Almaty is the largest city in Kazakhstan, with a high incidence and mortality from all types of cancer. The study aimed to analyze the cervical cancer incidence and mortality in Almaty in 2005-2022. Methods: Epidemiological analysis of cervical cancer incidence in Almaty for 2005-2022 was provided with analyzing reporting forms of documentation. Statistical processing was carried out using the SPSS v. 23.0 software. Results: Over the past 18 years (2005 to 2022), there has been an increase in the incidence rate from 16 to 18.3 per 100,000 female population and a consistently high mortality rate, which was 6.6 per 100,000 female population in 2022. In 2005, 108 women with cervical cancer were identified, of which 70% were patients with the first and second stages. In 2022, 198 cases of cervical cancer were registered, where the first stage accounts for 56.5%. In recent years, there has been an increase in the frequency of registration of new cases of cervical cancer starting from 30-34 years old, with a noticeable increase up to 40-44 years old. Conclusion: The results of this epidemiological study of cervical cancer incidence and mortality in Almaty indicate the need to improve and intensify screening among women of reproductive age, and introduce a vaccination and screening program using HPV testing.