年轻埃及妇女急性冠状动脉综合征的临床和血管造影特征

Timoor Hassan, A. Alaarag, Mahmoud Abuomar
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摘要

简介:虽然急性冠状动脉综合征(ACS)主要发生在50岁以上的个体,但年轻人也可能受到影响。年轻患者占ACS患者的2-10%,其中大多数为男性,而女性约占该人群的25%。方法:纳入ACS <45岁的患者,进行病史、临床检查、心电图、超声心动图及实验室检查,包括心酶、肾功能、全血细胞计数、血脂、血糖、肝功能。根据患者的诊断、病情和主治医生的决定,确定侵入性管理或医疗管理。对于行冠状动脉造影的患者,是否行PCI和支架植入术,是罪魁祸首病变还是完全血运重建术,都由手术人员决定。结果:该研究包括306名男性和92名女性。在高血压、血脂异常、缺血性心脏病或慢性肾病家族史方面无显著差异。女性患糖尿病的比例明显高于男性(40.2%),女性的身体质量指数明显高于男性(66%)。STEMI在男性中较多,不稳定型心绞痛在女性中较多。结论:与吸烟较少的男性相比,埃及女性ACS患者有更多的糖尿病发病率和更高的BMI。与男性的STEMI相比,她们更容易出现不稳定型心绞痛。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical and angiographic characteristics of young Egyptian women with acute coronary syndromes
Introduction: Although acute coronary syndrome (ACS) mainly occurs in individuals >50years, younger adults can be affected as well. Young patients represent 2-10% of patients with ACS, most of them are men while women constitute about 25% of this population. Methods : Patients with ACS <45years were included and were subjected to history taking, clinical examination, ECG, echocardiogram, and lab investigations including cardiac enzymes, renal functions, complete blood count, lipid profile, blood sugar, complete liver functions. Invasive management or medical management was determined depending on the diagnosis of the patient, his condition and the decision of the attending physician. For patient who underwent coronary angiography, decision of PCI and stenting and whether culprit lesion or complete revascularization was left for the operator. Results : The study included 306 men and 92 women. There was no significant difference regarding hypertension, dyslipidemia, family history of ischaemic heart disease or chronic kidney disease. Diabetes was significantly higher in women (40.2%) and body mass index was higher in women while smoking was significantly higher in men (66%). STEMI was more in men and unstable angina more in women. Conclusion : In Egyptian women with ACS, they have more incidence of diabetes and higher BMI compared to men with less incidence of smoking. They present more with unstable angina compared to more STEMI in men.
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