糖尿病足部感染患者无乳链球菌对β-内酰胺类抗生素耐药1例

Yolanda Pitra Kusumadewi, Afdina Melya Ganes Febiyanti, Ilma Tazkiya, Galang Ridha Allatief, Annisa Somaningtyas, Cicilia Widhi Astuti, Ika Puspitasari, K. Triyana, T. Wibawa, T. Nuryastuti
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引用次数: 0

摘要

糖尿病足感染是糖尿病患者常发生的并发症。金黄色葡萄球菌是糖尿病足感染中最常见的微生物。此外,凝固酶阴性的葡萄球菌、粪肠球菌、无乳链球菌和铜绿假单胞菌也可以被证实。糖尿病足感染的治疗通常需要很长时间,这可能会增加抗生素耐药性的风险。本文将介绍一个独特而有趣的病例无乳链球菌对β-内酰胺感染的抗性。病例描述:56岁男性,有长期糖尿病病史,但未服用抗糖尿病药物,既往无抗生素使用史。自2016年以来,他的右脚反复受伤,他经常治疗。创面拭子微生物培养获得对β-内酰胺类抗生素耐药的无乳链球菌、奇异变形杆菌和肺炎克雷伯菌3种细菌。结论:本病例检出对β-内酰胺类抗生素(青霉素、第三代和第四代头孢菌素)耐药的B族链球菌(无乳链球菌),提醒医务人员在合理使用抗生素时要更加谨慎谨慎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Streptococcus agalactiae is resistant to β-lactam antibiotics in a diabetic patient with foot infection: a case report
Introduction: Diabetic foot infection is a complication that often occurs in people with diabetes mellitus. Staphylococcus aureus is the most common microorganism found in diabetic foot infections. In addition, coagulase-negative staphylococci, Enterococcus faecalis, Streptococcus agalactiae, and Pseudomonas aeruginosa can also be demonstrated. Diabetic foot infection treatment usually takes a long time which may increasing the risk of antibiotic resistance. This article will present a unique and interesting case about Streptococcus agalactiae resistant to β-lactam infection. Case description: A 56-year-old man presented with a long history of diabetes mellitus but had not taken anti-diabetic drugs and had no history of previous use of antibiotics. Since 2016 his right foot had a recurring wound that he routinely treated. Microbiology culture of the wound swab obtained three bacteria namely Streptococcus agalactiae, Proteus mirabilis and Klebsiella pneumoniae which is resistant to β-lactam antibiotics. Conclusion: The identification of Group B Streptococcus bacteria (Streptococcus agalactiae) which are resistant to β-lactam antibiotics (penicillin, third and fourth generation cephalosporins) which were found in this case, reminds all medical personnel to be more careful and prudent in the rational use of antibiotics.
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