干眼症眼表冷却的初步研究

PhD, MCOptom Philip B. Morgan , MD, FRCOphth Andrew B. Tullo , PhD, MCOptom, FVCO, FAAO Nathan Efron
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引用次数: 46

摘要

采用红外热像仪测量11例干眼症患者和7例对照者睁眼时眼表温度的变化。在定性上,发现干眼症组的彩色编码热图是无序和不规则的。从数量上看,干眼组的温度下降速度(7s内0.88±0.23°C)比对照组(0.21±0.27°C)要快得多(P<0.0001)。这种更快的冷却速度可以用更大的蒸发速率和干眼睁开时眼表温度的增加来解释。这一观察结果,如果在一个更大的研究小组中得到证实,可能会为泪膜和干眼症治疗的分析提供一个新的、客观的、非侵入性的系统。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ocular surface cooling in dry eye — a pilot study

Infrared thermography was employed to measure the change in ocular surface temperature on eye opening within agroup of 11 dry-eye patients and seven control subjects. Qualitatively, the colour coded thermograms were found to be disorganised and irregular in the dry-eye group. Quantitatively, the decrease in temperature was found to be much more rapid in the dry-eye group (0.88 ± 0.23°C in 7s) compared with the control group (0.21 ± 0.27°C) (P<0.0001). This faster rate of cooling can be explained in terms of a greater evaporation rate and the increased ocular surface temperature on eye opening in a dry eye. This observation, if confirmed on a larger study group, potentially offers a new, objective, non-invasive system for analysis of the tear-film and dry-eye therapies.

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