Hemangioma and venous malformation are as different as an apple and orange!

The VM is one of these CVMs affecting the venous system, either alone or combined with other types of the CVMs (e.g., lymphatic malformation; AV‐shunting malformation). Hence, the VM remains one of the most difficult and confusing diagnostic and therapeutic enigmas together with the rest of CVMs due to the wide range of clinical presentation, unpredictable clinical course, erratic response to the treatment with high recurrence, and high morbidity by currently available conventional treatment.