{"title":"慢性肾病患儿sars - cov -2感染1例","authors":"O. Kovaleva, L. A. Lityaeva, O. Kaykova","doi":"10.22627/2072-8107-2022-21-2-67-72","DOIUrl":null,"url":null,"abstract":"Kidney disease and chronic renal failure are among the main comorbidities of the complicated course of COVID-19.Objective: to identify the clinical features of the course of a new coronavirus SARS-CoV-2-infection in a child aged 2 years 2 months with chronic kidney disease and dialysis-dependent renal failure.A new coronavirus infection typically began with a moderate intoxication syndrome and catarrhal symptoms, confirmed by the detection of SARS-CoV-2 RNA. Computed tomography of the chest revealed signs of bilateral pneumonia, 30% damage to the lung tissue. Progression occurred by the 4th day of hospitalization with the development of a multisystem inflammatory syndrome, including damage to the cardiovascular system of the digestive system against the background of the existing end-stage renal failure. Laboratory criteria for multisystem inflammatory syndrome were an increase procalcitonin, C-reactive protein, and ferritin. As a result of the developed multiple organ failure, a fatal outcome occurred.","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A case of SARS-CoV-2-infection in a child with chronic kidney disease\",\"authors\":\"O. Kovaleva, L. A. Lityaeva, O. Kaykova\",\"doi\":\"10.22627/2072-8107-2022-21-2-67-72\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Kidney disease and chronic renal failure are among the main comorbidities of the complicated course of COVID-19.Objective: to identify the clinical features of the course of a new coronavirus SARS-CoV-2-infection in a child aged 2 years 2 months with chronic kidney disease and dialysis-dependent renal failure.A new coronavirus infection typically began with a moderate intoxication syndrome and catarrhal symptoms, confirmed by the detection of SARS-CoV-2 RNA. Computed tomography of the chest revealed signs of bilateral pneumonia, 30% damage to the lung tissue. Progression occurred by the 4th day of hospitalization with the development of a multisystem inflammatory syndrome, including damage to the cardiovascular system of the digestive system against the background of the existing end-stage renal failure. Laboratory criteria for multisystem inflammatory syndrome were an increase procalcitonin, C-reactive protein, and ferritin. As a result of the developed multiple organ failure, a fatal outcome occurred.\",\"PeriodicalId\":9855,\"journal\":{\"name\":\"CHILDREN INFECTIONS\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-07-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"CHILDREN INFECTIONS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22627/2072-8107-2022-21-2-67-72\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"CHILDREN INFECTIONS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22627/2072-8107-2022-21-2-67-72","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A case of SARS-CoV-2-infection in a child with chronic kidney disease
Kidney disease and chronic renal failure are among the main comorbidities of the complicated course of COVID-19.Objective: to identify the clinical features of the course of a new coronavirus SARS-CoV-2-infection in a child aged 2 years 2 months with chronic kidney disease and dialysis-dependent renal failure.A new coronavirus infection typically began with a moderate intoxication syndrome and catarrhal symptoms, confirmed by the detection of SARS-CoV-2 RNA. Computed tomography of the chest revealed signs of bilateral pneumonia, 30% damage to the lung tissue. Progression occurred by the 4th day of hospitalization with the development of a multisystem inflammatory syndrome, including damage to the cardiovascular system of the digestive system against the background of the existing end-stage renal failure. Laboratory criteria for multisystem inflammatory syndrome were an increase procalcitonin, C-reactive protein, and ferritin. As a result of the developed multiple organ failure, a fatal outcome occurred.