在药物短缺的情况下，通过紧急抗菌药物管理有效地保存抗生素

Infection Control & Hospital Epidemiology Pub Date : 2016-12-05 DOI:10.1017/ice.2016.289

Kevin Hsueh, Maria M Reyes, Tamara Krekel, E. Casabar, D. Ritchie, Reza Jafarzadeh, Amanda J Hays, M. Lane, M. Durkin

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引用次数: 11

摘要

我们提出了抗菌药物管理计划(ASP)的第一个描述，用于成功地管理多种抗菌药物短缺。在不采取处方限制的情况下，美罗培南的使用率下降了69%，哌拉西林-他唑巴坦的使用率下降了73%。在短缺期间，住院死亡率下降(P=.03)，而住院时间不变。中华流行病学杂志，2017;38 (8):356 - 359

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Effective Antibiotic Conservation by Emergency Antimicrobial Stewardship During a Drug Shortage

We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam by 73%. During the shortage period, hospital mortality decreased (P=.03), while hospital length of stay remained unchanged. Infect Control Hosp Epidemiol 2017;38:356–359

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Infection Control & Hospital Epidemiology

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