埃及新型冠状病毒感染患者的生化变化

A. El-Adly, A. Wardany, Mohey Shikhoun
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摘要

新发现的冠状病毒病2019 (COVID-19),即快速传播的病毒性肺炎,目前正在发生大流行规模的爆发。由于该病的整体易感性,不同年龄组有不同的临床特征和检测结果。本研究的目的是描述不同年龄和性别群体的COVID-19实验室结果。该研究采用SARS-2 RNA逆转录聚合酶链反应(RT-PCR),对1100名典型感冒症状的个体进行了研究。据报告,这些病例中660例检测呈阳性,440例检测呈阴性,因此所有病例都进行了实验室检测。我们的研究显示,男性的COVID-19阳性率高于女性(215/660;67.4%),男性得分为445/660;32.6%)。COVID-19阳性和阴性病例的年龄无统计学差异。血细胞的血液学参数显示,感染COVID-19的患者和未感染COVID-19的患者的淋巴细胞差异显著,这些细胞在感染COVID-19时下降。在血红蛋白(Hgb百分比)、红细胞(rbc)、总白细胞(WBCS)、嗜碱性粒细胞、中性粒细胞、单核细胞和嗜酸性粒细胞以及血小板(PLTS)方面无显著差异。红细胞沉降率(ESR)并不重要,而COVID-19感染会增加铁蛋白和c反应蛋白。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biochemical changes in Egyptian patients infected with COVID-19
A pandemic-scale outbreak of the newly discovered coronavirus disease 2019 (COVID-19), fast-spreading viral pneumonia, is currently occurring. Due to the disease's overall vulnerability, different age groups have different clinical characteristics and test findings. The purpose of this study was to describe the COVID-19 laboratory results in various age and sex groups. Reverse transcriptase polymerase chain reaction (RT-PCR) for SARS-2 RNA was used in the study, which had 1100 individuals with typical cold symptoms. It was reported that 660 of these cases tested positive for the test, while 440 tested negatives, therefore all cases underwent laboratory testing. Our research revealed that males had higher COVID-19 positivity than females (215/660; 67.4%), with males scoring 445/660; 32.6%). Age does not statistically differ between COVID-19 positive and negative cases. Hematological parameters in blood cells revealed that Lymphocytes differ significantly between COVID-19-infected and uninfected patients as these cells decline in the presence of COVID-19 infection. There are no significant differences in hemoglobin (Hgb percent), red blood cells (RBCs), total white blood cells (WBCS), basophils, neutrophils, monocytes, and eosinophils, as well as blood platelets (PLTS). Erythrocyte sedimentation rate (ESR) is unimportant, whereas COVID-19 infection increases ferritin and C-reactive proteins.
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