Avinash Pore, G. Gaikwad, S. Hegade, Y. Jadhav, R. Mane, R. Kumbhar
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Analyzing the Impact of the Substituent on the Quinazolinone Schiff Base and the Interaction of the Fe (III) and Cr (III) with Different Quinazolinone Schiff Base for Antioxidant and Anti-inflammatory Activity
Abstract Schiff base and their Fe (III), Cr (III) complexes stood vetted for Antioxidant, Anti-inflammatory activities and docking study. Mixed ligand complexes had strong antioxidant and anti-inflammatory properties. Docking study of mixed ligand complexes reveals substantial binding affinity for COX2 and STAT3 receptors. The experimental and computational anti-inflammatory and antioxidant activity results are more consistent. GRAPHICAL ABSTRACT
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