Misato Wada, H. Kamata, N. Shima, Akari Ishikawa, Ryutaro Asai, Atsushi Nitta, Hidenao Kakehashi, Shihoko Nakano-Fujii, S. Matsuta, K. Sasaki, Tooru Kamata, H. Nishioka, A. Miki, Tasuku Murata, K. Ogata, H. Tsuchihashi, M. Katagi
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Application of probe electrospray ionization mass spectrometry to the analysis of poisons and drugs in adulterated foods and beverages
coexisting additives like surfactants or lactose were detected with high sensitivity in-dicating that the tested beverage had been adulterated by a foreign substance. Back-ground subtraction of the reference beverage mass spectra from those of the samples also enabled clearer and more reliable determination of the adulterants. The present-ed PESI MS method enables accurate screening in two minutes per sample with only a very simple pretreatment, applicable for large-scale screening of adulterants in foods and beverages. This method can serve as an extremely eŠective screening tool in combination with conˆrmatory instrumental analysis methods for identifying foreign
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