抑郁症、患者特征和依恋类型:不同种族初级保健样本中药物治疗依从性的相关因素和中介因素

Lisa M. Hooper, S. Tomek, D. Roter, K. Carson, George C. T. Mugoya, L. Cooper
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引用次数: 9

摘要

与抑郁症状学和最佳治疗结果(包括药物治疗依从性)相关的问题的深度和广度早已在文献中得到记录。缺少关于哪些因素和患者特征可能导致缺乏药物治疗依从性的明确解释。本研究的两个目的是检验抑郁症、患者特征和患者依恋类型对药物治疗依从性的预测强度,并考虑依恋类型在多大程度上调解抑郁症和药物治疗依从性之间的关系。方法本研究的参与者是237名不同种族的美国初级保健患者,他们被诊断为高血压,并参加了一项临床试验。评估抑郁、患者特征、依恋类型和药物治疗依从性。结果与我们的四个假设部分一致,发现了以下结果:(a)美国黑人,年轻,未婚和贫穷的患者有较低的药物治疗依从性(b)抑郁症与较低的自我报告药物依从性显著相关;(c)不安全解除型依恋类型与较低的药物依从性相关;(d)不安全型依恋类型通过加剧抑郁与药物治疗依从性之间的负相关来调节抑郁与药物治疗依从性之间的关系。结论:医生和其他初级保健提供者应考虑抑郁症状、患者特征和依恋类型如何影响他们提出的治疗方案,以及患者对这些治疗方案的坚持程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Depression, patient characteristics, and attachment style: correlates and mediators of medication treatment adherence in a racially diverse primary care sample
Background The depth and breadth of problems related to depressive symptomatology and optimal treatment outcomes, including medication treatment adherence, have long been documented in the literature. Missing are clear explanations as to what factors and patient characteristics may account for lack of medication treatment adherence. Objectives The two objectives of the current study were to examine the predictive strength of depression, patient characteristics, and patient attachment style regarding medication treatment adherence and to consider the extent to which attachment styles mediate the relation between depression and medication treatment adherence. Method Participants in the present study were 237 racially diverse American primary care patients with a diagnosis of hypertension who were participants in a clinical trial. Depression, patient characteristics, attachment style, and medication treatment adherence were assessed. Results Partly consistent with our four hypotheses, the following results were found: (a) Black American, younger, never married, and poorer patients had lower medication treatment adherence (b) depression was significantly associated with lower self-reported medication adherence; (c) insecure–dismissing attachment style was related to lower medication adherence; and (d) insecure–dismissing attachment style mediates the relation between depression and medication treatment adherence by exacerbating the negative association. Conclusion Physicians and other primary care providers should consider how depressive symptomatology, patient characteristics, and attachment style may inform the treatment plans they put forward and the extent to which patients may adhere to those treatment plans.
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