儿童非酒精性脂肪肝的心血管风险:最新进展

Q Medicine

Clinical Lipidology Pub Date : 2015-08-01 DOI:10.2217/clp.15.26

S. Baskar, S. Jhaveri, N. Alkhouri

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引用次数: 3

摘要

非酒精性脂肪性肝病(NAFLD)是发达国家儿童慢性肝病最常见的形式。NAFLD已经上升到流行病的程度，与儿童肥胖相当。越来越明显的是，NAFLD与心血管疾病(CVD)密切相关，心血管疾病是成人NAFLD人群死亡的主要原因。对于照顾儿童的医生来说，认识到儿童NAFLD作为CVD独立危险因素的潜在作用是非常重要的。儿童时期是可以检测到亚临床心血管疾病的时期，这给了我们阻止或逆转疾病进程的潜在能力。在这篇综述中，我们讨论了最近的证据表明儿童NAFLD与CVD和潜在的致病联系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cardiovascular risk in pediatric nonalcoholic fatty liver disease: recent advances

Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common form of pediatric chronic liver disease in developed countries. NAFLD has risen to epidemic proportions paralleling that of childhood obesity. It is becoming increasingly evident that NAFLD is strongly linked with cardiovascular disease (CVD), which is the leading cause of mortality in the adult NAFLD population. It is very important for physicians caring for children being cognizant of the potential role of childhood NAFLD as an independent risk factor for CVD. Childhood is a time period where subclinical CVD can be detected, giving us the potential ability to halt or reverse the disease process. In this review, we discuss recent evidence linking childhood NAFLD to CVD and potential pathogenic links.

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来源期刊

Clinical Lipidology 生物-生化与分子生物学

CiteScore

0.44

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal of Clinical Lipidology is published to support the diverse array of medical professionals who work to reduce the incidence of morbidity and mortality from dyslipidemia and associated disorders of lipid metabolism. The Journal''s readership encompasses a broad cross-section of the medical community, including cardiologists, endocrinologists, and primary care physicians, as well as those involved in the treatment of such disorders as diabetes, hypertension, and obesity. The Journal also addresses allied health professionals who treat the patient base described above, such as pharmacists, nurse practitioners and dietitians. Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. While preference is given to material of immediate practical concern, the science that underpins lipidology is forwarded by expert contributors so that evidence-based approaches to reducing cardiovascular and coronary heart disease can be made immediately available to our readers. Sections of the Journal will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.