老年男性和女性意外跌倒的危险因素:来自英国老龄化纵向研究的发现

L. Westbury, C. Gale, C. Cooper, Emily Dennison
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引用次数: 1

摘要

跌倒是老年人特别是妇女致残和死亡的一个主要原因。横断面调查表明,与跌倒史相关的一些风险因素可能是性别特异性的,但意外跌倒的风险因素在性别之间是否存在差异尚不清楚。这项研究调查了意外跌倒的危险因素,以及这些因素在男性和女性之间是否存在差异。方法参与者为3298名男性和女性(第4波60岁及以上),他们参加了英国老龄化纵向研究第4 - 6波的调查。在第4阶段,他们提供了关于以前跌倒、社会人口、生活方式、行为和医疗因素的信息,并对他们的身体和认知功能进行了评估。在第5波和第6波收集了四年随访期间自我报告的跌倒事件的数据。基线特征与事件跌倒之间关联的相对风险(RR)使用具有稳健方差估计的性别特异性泊松回归模型推导。与跌倒相关的因素(p<0.20)被纳入性别特异性相互调整模型。对男性和女性分别进行了分析,并根据第4波之前的跌倒情况调整了相对风险。结果:总体而言,633名(41.8%)男性和863名(48.4%)女性在第4波和第6波之间经历了意外跌倒。在相互调整的模型中,年龄是唯一与男女意外跌倒风险增加相关的因素。一些因素仅预测一种性别的跌倒,即女性更多的抑郁症状(RR (95% CI) 1.03(1.01, 1.06)),失禁(1.11(1.00,1.24))和从未结婚(1.26(1.03,1.53)),男性更多的合病(1.05(1.00,1.09)),更高的疼痛水平(1.11(1.04,1.18))和较差的平衡(1.25(1.05,1.49))。其中,根据相互作用检验,只有疼痛、平衡和共病与跌倒风险之间的关系在性别上有显著差异(p<0.05)。结论年龄越大,男女发生跌伤的风险越高。然而,关于疼痛、平衡和合并症的关联因性别而异。该研究的优势包括样本量大,而且它代表了60岁及以上的社区居住的英国人口。然而,一个潜在的弱点是,调查问卷中没有定义什么是“跌倒”。这项研究将为制定干预措施提供信息,以减少老年人跌倒的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
P59 Risk factors for incident falls in older men and women: findings from the english longitudinal study of ageing
Background Falls are a major cause of disability and death among older people, particularly women. Cross-sectional surveys suggest that some risk factors associated with a history of falls may be sex-specific but whether risk factors for incident falls differ between the sexes is unclear. This study investigated risk factors for incident falls and whether they differ between men and women. Methods Participants were 3298 men and women (aged 60 years and over at Wave 4) who took part in the Waves 4–6 surveys of the English Longitudinal Study of Ageing. At Wave 4, they provided information on previous falls, sociodemographic, lifestyle, behavioural and medical factors, and had their physical and cognitive function assessed. Data on self-reported incident falls during the four-year follow-up period were collected at Waves 5 and 6. Relative risks (RR) for the association between baseline characteristics and incident falls were derived using sex-specific Poisson regression models with robust variance estimation. Factors associated with falling (p<0.20) were included in sex-specific mutually-adjusted models. Analyses were performed among men and women separately and relative risks were adjusted for previous falls before Wave 4. Results Overall, 633 (41.8%) men and 863 (48.4%) women experienced an incident fall between Waves 4 and 6. In mutually-adjusted models, older age was the only factor associated with increased risk of incident falls in both sexes. Some factors were only predictive of falls in one sex, namely more depressive symptoms (RR (95% CI) 1.03 (1.01, 1.06)), incontinence (1.11 (1.00,1.24)) and never having married in women (1.26 (1.03,1.53)), and greater comorbidity (1.05 (1.00,1.09)), higher levels of pain (1.11 (1.04,1.18)) and poorer balance (1.25 (1.05,1.49)) in men. Of these, only the relationships between pain, balance and comorbidity and falls risk differed significantly (p<0.05) by gender according to interaction tests. Conclusion Older age was associated with increased risk of incident falls in both sexes. However, associations regarding pain, balance and comorbidity differed by gender. Strengths of the study include the large sample size and the fact that it is representative of the community-dwelling English population aged 60 years and over. However, one potential weakness is that there was no definition in the questionnaire of what constituted a fall. This research will inform the development of interventions to reduce the risk of falls among older people.
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