用于纸基分析装置的聚合物组件

M. D. M. González del Campo, Andreu Vaquer, R. de la Rica
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引用次数: 4

摘要

近年来,从可穿戴设备到一次性测试条和生物传感器,纸已成为开发不同类型传感器的重要基板材料。同时,一种基于聚合物的工具箱已经出现,以便为这些基于纸张的分析设备添加额外的功能。在这篇文章中,从最近的文献中编译的例子显示了基于不同方法打印不渗透聚合物屏障的微流控系统,以及在基于纸的分析平台中实现电化学,荧光和比色聚合物传感器。外部驱动或可溶解聚合物阀门和储层,分析物浓缩器和分离装置,以及印刷在纸基上的基于聚合物的识别元件(分子印迹聚合物)也进行了综述。这项研究揭示了开发复杂的片上实验室设备的多种可能性,这些设备中实现了不同的聚合物基组件。用普通印刷方法对这些聚合物进行图案化的能力,不需要专门的设备,为大规模生产这种先进的纸基分析设备铺平了道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Polymer Components for Paper‐Based Analytical Devices
In recent years, paper has become an essential substrate material for developing different types of sensors, from wearable devices to single‐use test strips and biosensors. In parallel, a polymer‐based toolbox has emerged in order to add additional functions to these paper‐based analytical devices. In this article, examples are compiled from the recent literature showing microfluidic systems based on printing impermeable polymer barriers with different methods as well as the implementation of electrochemical, fluorescent, and colorimetric polymer‐based transducers in paper‐based analytical platforms. Externally actuated or dissolvable polymer valves and reservoirs, analyte concentrators, and separation devices, as well as polymer‐based recognition elements (molecularly imprinted polymers) printed on paper substrates are also reviewed. The search has revealed a plethora of possibilities for developing complex lab‐on‐chip devices implementing different polymer‐based components in them. The ability of patterning these polymers with common printing methods that do not require specialized facilities paves the way for mass producing this kind of advanced paper‐based analytical device.
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