Paola Tieppo, M. Papadopoulou, Deborah Gatti, N. McGovern, J. Chan, F. Gosselin, Glenn Goetgeluk, K. Weening, Ling Ma, N. Dauby, Alexandra Cogan, C. Donner, F. Ginhoux, B. Vandekerckhove, D. Vermijlen
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The human fetal thymus generates invariant effector γδ T cells
Tieppo et al. show that the human fetal thymus generates invariant γδ T cells with programmed effector functions. This is due to an intrinsic property of fetal HSPCs caused by high expression of the RNA-binding protein Lin28b.
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