微摄影测量作为表征药物剂型溶出行为的工具

British Journal of Pharmacy Pub Date : 2018-07-17 DOI:10.5920/bjpharm.2017.22

A. D’Angelo, M. Reading, Milan D Antonjievic

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引用次数: 0

摘要

该项目的目的是开发一种创新的分析技术，用于药物剂型的三维化学制图，通过同时的地形特征和固体药物输送系统的溶解分析。利用微摄影测量学在商业固体给药系统分析中的应用结果，对所开发的仪器进行了优化。本文给出了该方法在糖衣片溶出度测定中的应用结果。

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Micro-photogrammetry as a tool for characterisation of dissolution behaviour of pharmaceutical dosage forms

The aim of this project is to develop an innovative analytical technique for the 3D chemical mapping of pharmaceutical dosage forms, via simultaneous topographic characterisation and dissolution analysis of solid drug delivery systems. The developed apparatus was optimised using the results obtained from the application of micro-photogrammetry to the analysis of commercial solid drug delivery systems. Results of the application of the developed method on the dissolution of a sugarcoated tablet sample are here presented.

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British Journal of Pharmacy

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