中心性胰腺切除术:风险与益处争论的中心

N. Machado
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引用次数: 0

摘要

中央胰腺切除术(Central pancreatic ectomy, CP)是一种保留实质的手术,涉及胰腺的节段性切除[1-4]。这是最适合提倡切除良性和低度恶性病变的,起源于胰腺的颈部和近端[4-13]。这种病变传统上需要胰十二指肠切除术或远端胰切除术[4,6]。这些手术虽然在肿瘤学上是合理的,但需要切除相当数量的正常实质。然而,最近的文献经常报道对这种低级别或良性肿瘤进行CP治疗[1-13]。与传统切除相比,CP能显著保留正常胰腺实质,并被认为能更好地保存胰腺功能,且发病率和死亡率可接受[3-7,12]。然而,争论的焦点是,CP的好处和长期/短期并发症是什么,好处是否大于风险?
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Central Pancreatectomy: A Center of Debate of Risk versus Benefit
Central Pancreatectomy (CP) is a parenchyma sparing operation, which involves segmental resection of the pancreas [1-4]. This is most appropriate to advocate in removal of benign and low-grade malignant lesions, arising from the neck and proximal body of the pancreas [4-13]. Such lesions would have traditionally required pancreaticoduodenectomy or distal pancreatectomy [4,6]. These procedures while oncologically sound, involves resection of considerable amount normal parenchyma. Recent literature however has frequent reports of CP being performed for such low grade or benign tumours [1-13]. CP, when compared to traditional resection, achieves significant sparing of normal pancreatic parenchyma and is believed to offer better preservation of pancreatic function with acceptable morbidity and mortality [3-7,12]. The debate however is, what are the benefits and long/short term complications of CP and does the benefit outweigh the risk?
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