用于医疗保健和环境应用的有机纳米机电传感器系统

V. Rao
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引用次数: 0

摘要

有机场效应晶体管和聚合物微悬臂梁是两类在生化传感领域具有潜在应用前景的有机传感器。以区域规则聚3-己基噻吩(r - p3ht)和六氟-2-丙醇取代聚硅氧烷(SXFA)为有机层的有机场效应晶体管(ofet)已被用于爆炸性气体的检测,对1,3,5-三硝基-1,3,5-三氮杂环己烷(RDX)的灵敏度小于70 ppt,对2,4,6-三硝基甲苯(TNT)的灵敏度小于100 ppt[1 - 3]。压电和压电聚合物复合微悬臂梁已被证明是生物化学检测的敏感和经济有效的平台[4-12]。OFET和聚合物悬臂平台的集成可以为选择性是关键要求的传感带来正交性。我们最近通过在聚合物纳米机械悬臂[6]表面集成应变敏感的有机场效应晶体管(OFET)实现了这一目标。这种被称为“有机CantiFET”的传感器显示出迄今为止报道的最高挠度和表面应力灵敏度,并为实现各种应用的高灵敏度但选择性低成本聚合物传感器开辟了机会。
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Organic nano-electro-mechanical-sensor systems for healthcare and environmental applications
Organic field effect transistors and polymer microcantilevers are two classes of organic sensors with potential applications in biochemical sensing. The organic field effect transistors (OFETs) with region regular poly3-hexylthiophene(rr-P3HT) and hexafluoro-2-propanol-substituted polysiloxane (SXFA) as an organic layer, have been used for detection of explosive vapors with excellent sensitivity of less than 70 ppt for 1,3,5-trinitro-1,3,5-triazacyclohexane (RDX) and less than 100 ppt for 2,4,6-trinitrotoluene (TNT) [1–3]. Piezo-resistive & piezo-electric polymer composite microcantilevers have been demonstrated as sensitive and cost effective platforms for bio-chemical detection [4–12]. Integration of the OFET and the polymer cantilever platform can bring orthogonality to the sensing where selectivity is a critical requirement. We have recently achieved this by integrating a strain sensitive organic field effect transistor (OFET) on the surface of a polymer nanomechanical cantilever [6]. This sensor named as the “Organic CantiFET” shows the highest deflection and surface stress sensitivity reported till date and opens up opportunities for realizing highly sensitive yet selective low cost polymer sensors for a variety of applications.
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