COPD严重程度阶段是否会改变合并症模式?

S. Popović-Grle, Višnja Dukić, Josipa Škugor, D. Oroz, D. Ogresta
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引用次数: 1

摘要

目的:估计慢性阻塞性肺疾病(COPD)患者合并症的频率和类型的差异,根据全球慢性阻塞性肺疾病倡议(GOLD),按COPD严重程度分期从1到4分组。数据对象和方法:本研究纳入168例COPD患者,每个GOLD期患者的比例相等(GOLD I期47例,GOLD II期43例,GOLD III期41例,GOLD IV期37例)。所有数据对象,106名男性和62名女性(年龄中位数为66岁),都是根据连续到达萨格勒布大学医院中心Jordanovac肺部疾病临床中心进行体检的情况进行处理的。结果:无论GOLD分期如何,最常见的合并症是心血管疾病,占60.1%。其次是肺炎(25.6%)、焦虑和抑郁(16.1%)、糖尿病(12.5%)和骨质疏松(11.9%)。最常见的恶性疾病是膀胱癌。随着GOLD分期的严重程度,患肺炎的患者比例持续增加。结论:GOLDⅰ期平均共病1.5例,GOLDⅱ期平均共病1.8例,GOLDⅲ期平均共病2.1例,GOLDⅳ期平均共病1.7例。这表明,根据GOLD分期,合并症的数量差异可能是显著的。这一初步结果经统计学卡方检验证实,显著性水平为5% (α = 0.05),而GOLD分期的合并症类型差异无统计学意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Does COPD severity stage change comorbidities pattern?
Aim: Estimation of the difference in frequency and type of comorbidities in patients with chronic obstructive pulmonary disease (COPD), grouped by COPD severity stages according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD), from 1 to 4. The data subjects and methods: This study included 168 COPD patients with an equal share of patients in each GOLD stage (GOLD I 47 subjects, GOLD II 43, GOLD III 41 and GOLD IV 37 subjects). All data subjects, 106 men and 62 women (median age 66), were processed according to the successive arrival at the Clinical Center for Pulmonary Diseases Jordanovac, University Hospital Center Zagreb, for their medical examination. Results: The most common comorbidities were cardiovascular diseases with 60.1%, regardless of the GOLD stage. These are followed by pneumonia in 25.6% of COPD patients, anxiety and depression in 16.1%, diabetes in 12.5% and osteoporosis in 11.9% of the COPD patients. The most frequent malignant disease was the urinary bladder cancer. The share of the patients who suffered from pneumonia is consistently increasing with the severity of GOLD stages. Conclusion: The average number of comorbidities in GOLD I stage was 1.5, in GOLD II stage 1.8, GOLD III stage 2.1 and in GOLD IV stage 1.7. This suggests that the difference in the number of comorbidities according to the GOLD stages could be significant. This preliminary result was confirmed by a statistical chi-squared test with a significance level of 5% ( α = 0.05), whereas the difference in the types of comorbidities according to the GOLD stages was not statistically significant.
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