S. Nimesh, S. Bharat, Mehta Abhay, S. Sandeep, P. Archna
{"title":"维生素D: COVID-19治疗或预防的综述和建议证据","authors":"S. Nimesh, S. Bharat, Mehta Abhay, S. Sandeep, P. Archna","doi":"10.23937/2469-567x/1510064","DOIUrl":null,"url":null,"abstract":"WHO declared SARS-CoV-2 a worldwide pandemic. The ambitions of this paper are to assess if there is any affiliation between mean levels of \ndiet D in various countries and cases respectively mortality because of COVID-19. Low vitamin d repute in winter allows viral epidemics. During \niciness, those who do not take nutrition d supplements are possibly to have low serum 25-hydroxyvitamin D [25 (OH)D] concentrations. Nutrition \nD can reduce the chance of viral epidemics and pandemics in numerous approaches. First, better 25 (OH)D concentrations lessen the chance of \nmany continual illnesses, together with cancers, cardiovascular sickness, continual Respiratory Tract Infections (RTIs), diabetes mellitus, and high \nblood pressure. Patients with continual sicknesses have a drastically higher threat of dying from RTIs than otherwise wholesome human beings. \nIn the 2D, nutrition D reduces the risk of Acute Respiratory Tract Infections (ARTIs) through three mechanisms: keeping tight junctions, killing \nenveloped viruses through induction of cathelicidin and defensins, and reducing the production of proinflammatory cytokines by means of the \ninnate immune machine, thereby decreasing the hazard of a cytokine hurricane leading to pneumonia. Observational and supplementation trials \nhave pronounced higher 25 (OH)D concentrations associated with decreased threat of dengue, hepatitis, herpes virus, hepatitis b, and c viruses, \nhuman immunodeficiency virus, influenza, breathing syncytial virus infections, and pneumonia. Effects of a community discipline trial pronounced \nherein indicated that 25 (OH)D concentrations above 50 ng/ml (125 nmol/l) vs. <20 ng/ml have been associated with a 27% discount in influenza- \nlike ailments. From the available evidence, we hypothesize that raising serum 25 (OH)D concentrations through nutrition d supplementation may \nwant to lessen the occurrence, severity, and chance of dying from influenza, pneumonia, and the cutting-edge COVID-19 epidemic.","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Vitamin D: A Review and Proposed Evidence for Treatment or Prevention in COVID-19\",\"authors\":\"S. Nimesh, S. Bharat, Mehta Abhay, S. Sandeep, P. Archna\",\"doi\":\"10.23937/2469-567x/1510064\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"WHO declared SARS-CoV-2 a worldwide pandemic. The ambitions of this paper are to assess if there is any affiliation between mean levels of \\ndiet D in various countries and cases respectively mortality because of COVID-19. Low vitamin d repute in winter allows viral epidemics. During \\niciness, those who do not take nutrition d supplements are possibly to have low serum 25-hydroxyvitamin D [25 (OH)D] concentrations. Nutrition \\nD can reduce the chance of viral epidemics and pandemics in numerous approaches. First, better 25 (OH)D concentrations lessen the chance of \\nmany continual illnesses, together with cancers, cardiovascular sickness, continual Respiratory Tract Infections (RTIs), diabetes mellitus, and high \\nblood pressure. Patients with continual sicknesses have a drastically higher threat of dying from RTIs than otherwise wholesome human beings. \\nIn the 2D, nutrition D reduces the risk of Acute Respiratory Tract Infections (ARTIs) through three mechanisms: keeping tight junctions, killing \\nenveloped viruses through induction of cathelicidin and defensins, and reducing the production of proinflammatory cytokines by means of the \\ninnate immune machine, thereby decreasing the hazard of a cytokine hurricane leading to pneumonia. Observational and supplementation trials \\nhave pronounced higher 25 (OH)D concentrations associated with decreased threat of dengue, hepatitis, herpes virus, hepatitis b, and c viruses, \\nhuman immunodeficiency virus, influenza, breathing syncytial virus infections, and pneumonia. Effects of a community discipline trial pronounced \\nherein indicated that 25 (OH)D concentrations above 50 ng/ml (125 nmol/l) vs. <20 ng/ml have been associated with a 27% discount in influenza- \\nlike ailments. From the available evidence, we hypothesize that raising serum 25 (OH)D concentrations through nutrition d supplementation may \\nwant to lessen the occurrence, severity, and chance of dying from influenza, pneumonia, and the cutting-edge COVID-19 epidemic.\",\"PeriodicalId\":14458,\"journal\":{\"name\":\"International Journal of Virology and AIDS\",\"volume\":\"6 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Virology and AIDS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23937/2469-567x/1510064\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Virology and AIDS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23937/2469-567x/1510064","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Vitamin D: A Review and Proposed Evidence for Treatment or Prevention in COVID-19
WHO declared SARS-CoV-2 a worldwide pandemic. The ambitions of this paper are to assess if there is any affiliation between mean levels of
diet D in various countries and cases respectively mortality because of COVID-19. Low vitamin d repute in winter allows viral epidemics. During
iciness, those who do not take nutrition d supplements are possibly to have low serum 25-hydroxyvitamin D [25 (OH)D] concentrations. Nutrition
D can reduce the chance of viral epidemics and pandemics in numerous approaches. First, better 25 (OH)D concentrations lessen the chance of
many continual illnesses, together with cancers, cardiovascular sickness, continual Respiratory Tract Infections (RTIs), diabetes mellitus, and high
blood pressure. Patients with continual sicknesses have a drastically higher threat of dying from RTIs than otherwise wholesome human beings.
In the 2D, nutrition D reduces the risk of Acute Respiratory Tract Infections (ARTIs) through three mechanisms: keeping tight junctions, killing
enveloped viruses through induction of cathelicidin and defensins, and reducing the production of proinflammatory cytokines by means of the
innate immune machine, thereby decreasing the hazard of a cytokine hurricane leading to pneumonia. Observational and supplementation trials
have pronounced higher 25 (OH)D concentrations associated with decreased threat of dengue, hepatitis, herpes virus, hepatitis b, and c viruses,
human immunodeficiency virus, influenza, breathing syncytial virus infections, and pneumonia. Effects of a community discipline trial pronounced
herein indicated that 25 (OH)D concentrations above 50 ng/ml (125 nmol/l) vs. <20 ng/ml have been associated with a 27% discount in influenza-
like ailments. From the available evidence, we hypothesize that raising serum 25 (OH)D concentrations through nutrition d supplementation may
want to lessen the occurrence, severity, and chance of dying from influenza, pneumonia, and the cutting-edge COVID-19 epidemic.