不是最简单的甲状腺肿

Григорий Анатольевич Герасимов
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引用次数: 2

摘要

2020年是美国医生D. Marine和O. Kimball发表一项经典研究的百年纪念,该研究是关于预防俄亥俄州阿克伦儿童地方性甲状腺肿的有效性。虽然甲状腺肿从远古时代就为人所知,但确定甲状腺的正常大小仍然是一个问题,否则甲状腺肿的诊断仍然是非常主观的。例如,在过去的20年里,瑞典没有一例地方性甲状腺肿的病例,这并不奇怪:该国在几十年前就消除了这种病理,尿碘浓度中位数表明了最佳碘摄入量。瑞典儿童散发性甲状腺肿的病例也很少见,每年不超过6-8例。但在白俄罗斯,人口相同(约1000万),每年记录的儿童甲状腺肿病例约2900例,既有地方性的,也有散发性的,尽管事实上,由于自本世纪初以来广泛使用碘盐,没有碘缺乏症。然而,儿童甲状腺肿的发病率在过去20年中已经下降了许多倍,但仍然比俄罗斯高3倍,在俄罗斯,如果在有限的范围内进行碘预防。从白俄罗斯、瑞典和俄罗斯的经验中,我们看到,在评估与碘缺乏有关的甲状腺肿和其他甲状腺疾病发病率的数据时,主要不应该是绝对数字,而应该是这些指标在过去几年的趋势。俄罗斯的内分泌学家应更积极地利用这些资料,以评估区域和联邦各级预防措施的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Не самый простой зоб
The year 2020 marks the centenary of the publication of a classic study by American physicians D. Marine and O. Kimball on the effectiveness of endemic goiter prevention in children in Akron, Ohio. Although goiter has been known from immemorial times, there is still a problem with determining the normal size of the thyroid gland, without which the diagnosis of goiter remains extremely subjective. For example, in Sweden over the past 20 years, not a single case of endemic goiter has been registered, which is not surprising: the country eliminated this pathology decades ago, and the median urinary iodine concentration indicates the optimal iodine intake. Cases of sporadic goiter in children in Sweden are also rare — no more than 6–8 per year. But in Belarus, with the same population (about 10 million), about 2900 cases of goiter in children, both endemic and sporadic, are recorded annually despite the fact that, due to the extensive use of iodized salt since the beginning of the 2000s, there is no iodine deficiency. The incidence of goiter in children, however, having decreased many times over the past 20 years, remains 3 times higher than in Russia, where iodine prophylaxis, if carried out on a limited scale. From the experience of Belarus, Sweden and Russia, we see that the main thing when assessing data on the incidence of goiter and other thyroid diseases associated with iodine deficiency should be not absolute numbers, but the trend of these indicators over the past years. This information should be more actively used by endocrinologists in Russia to assess the effectiveness of preventive measures both at the regional and federal levels.
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