G. Octavius, Tan G. H. Handoko, C. L. Budiputri, M. Muljono, A. Juliansen
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引用次数: 0
摘要
热性惊厥(FS)是最常见的儿童神经系统疾病之一,影响2 - 5%的6个月至5岁儿童。在2008年至2010年期间,印度尼西亚几乎有一半患有FS的儿童复发。各种因素与FS复发的潜在预测因素有关。然而,现有数据报告的结果不一致。考虑到FS的高复发率,本研究旨在确定和评估预测FS复发的因素。横断面研究在力宝村西罗亚总医院进行。研究时间为2018年12月至2019年12月,数据通过病历获取。60名参与者中,41.7%有复发性FS。入院前未直肠给予安定(优势比[OR] = 6.42;95%可信区间[CI]: 1.20 ~ 34.2, p = 0.027)是FS复发的预测因素,而女性(OR = 0.23;95% CI: 0.64-0.80, p = 0.025),第一次FS持续时间较短(OR = 0.21;95% CI 0.06 ~ 0.69, p = 0.008)是FS复发的保护因素。识别预测FS复发的因素是临床医生的有力工具。本研究显示,入院前未使用直肠安定与FS复发风险相关,而FS持续时间较短和女性是FS复发的保护因素。
Factors Predicting the Recurrence of Febrile Seizure in Siloam General Hospital: A Descriptive Analysis
Abstract Febrile seizure (FS) is one of the most common pediatric neurologic disorders, affecting 2 to 5% of children between 6 months and 5 years. In 2008 to 2010, almost half of children with FS in Indonesia experienced recurrences. Various factors have been related to potential predictors for FS recurrence. However, available data reported inconsistent results. Considering its high recurrence rate, this study aimed to determine and assess the factors predicting the recurrence of FS. A cross-sectional study was done in Siloam General Hospital, Lippo Village. The study period was from December 2018 to December 2019, and data were obtained through medical records. Out of 60 participants, 41.7% had recurrent FS. No administration of rectal diazepam before admission (odds ratio [OR] = 6.42; 95% confidence interval [CI]: 1.20–34.2, p = 0.027) was a predictive factor of recurrent FS, while female sex (OR = 0.23; 95% CI: 0.64–0.80, p = 0.025) and shorter duration of the first FS (OR = 0.21; 95% CI 0.06–0.69, p = 0.008) were protective factors of recurrent FS. Identification of factors predicting the recurrence of FS is a powerful tool for clinicians. This study showed that no administration of rectal diazepam before admission was correlated with the risk of FS recurrence, while shorter duration of FS and female sex were protective factors of recurrent FS.
期刊介绍:
The Journal of Pediatric Epilepsy is an English multidisciplinary peer-reviewed international journal publishing articles on all topics related to epilepsy and seizure disorders, epilepsy surgery, neurology, neurosurgery, and neuropsychology in childhood. These topics include the basic sciences related to the condition itself, the differential diagnosis, natural history, and epidemiology of seizures, and the investigation and practical management of epilepsy (including drug treatment, neurosurgery and non-medical and behavioral treatments). Use of model organisms and in vitro techniques relevant to epilepsy are also acceptable. Journal of Pediatric Epilepsy provides an in-depth update on new subjects and current comprehensive coverage of the latest techniques used in the diagnosis and treatment of childhood epilepsy.