甘精胰岛素加阿卡波糖片治疗老年糖尿病的临床疗效及糖化血红蛋白分析

Hua-Yi Lu
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引用次数: 0

摘要

目的:分析甘精胰岛素加阿卡波糖片治疗老年糖尿病的临床疗效及糖化血红蛋白分析。方法:选取台州市中西医结合医院2021年1月~ 2022年12月收治的患者80例,随机分为两组(40例/组)。对照组患者给予阿卡波糖片治疗,观察组患者给予甘精胰岛素联合阿卡波糖片治疗。比较两组的临床疗效。结果:两组患者治疗前血糖水平及生活质量评分差异均无统计学意义(P > 0.05)。观察组总有效率(97.5%)显著高于对照组(85.0%);观察组患者血糖指标均显著低于对照组;观察组患者生活质量评分高于对照组(P < 0.05)。结论:老年糖尿病具有反复发作的特点。老年人经常患有慢性疾病,如心血管疾病和呼吸系统疾病,这使得在治疗中很难达到预期的效果。因此,有必要探索新的治疗方法来管理老年糖尿病。甘精胰岛素是一种新型胰岛素类似物,可持续24小时,有效控制患者血糖水平。研究表明,甘精胰岛素能长期有效调节糖尿病患者的血糖水平,显著降低空腹血糖,减少低血糖引起的并发症。另一方面,阿卡波糖片是一种α -葡萄糖苷酶抑制剂,可以防止淀粉分解成糖,从而降低餐后血糖水平。对于糖尿病患者,特别是以淀粉为主食的糖尿病患者,阿卡波糖是一种合适的药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical Effects of Insulin Glargine and Acarbose Tablets in the Treatment of Diabetes Mellitus in the Elderly and Analysis of Glycosylated Hemoglobin
Objective: To analyze the clinical effects of insulin glargine and acarbose tablets in the treatment of diabetes mellitus in the elderly and the analysis of glycosylated hemoglobin. Methods: Patients (80 cases) from Taizhou City Hospital of Traditional Chinese and Western Medicine (January 2021–December 2022) were randomly divided into two groups (40 cases/group). Patients in the control group were treated with acarbose tablets, whereas those in the observation group were treated with insulin glargine and acarbose tablets. The clinical effects were compared. Results: The difference in blood glucose level and quality of life score between the two groups before treatment was insignificant (P > 0.05). The total effective rate (97.5%) of the observation group was significantly higher than that of the control group (85.0%); the blood sugar indices of the observation group were significantly lower than those of the control group; and the observation group scored higher in the quality-of-life scale than the control group (P < 0.05). Conclusion: Diabetes in elderly is characterized by repeated attacks. The elderly often suffers from chronic diseases, such as cardiovascular disease and respiratory system disease, making it is challenging to achieve the desired effect in treatment. Therefore, it is necessary to explore new treatment methods for the management of diabetes in the elderly. Insulin glargine is a new type of insulin analog, which can last for 24 hours, effectively controlling patients’ blood sugar level. According to research, insulin glargine can effectively regulate the blood sugar level of diabetic patients for an extended period of time, significantly lower the fasting blood sugar, and reduce the complications caused by hypoglycemia. Acarbose tablet, on the other hand, is an alpha-glucosidase inhibitor, which prevents the breakdown of starch into sugar, thereby reducing postprandial blood sugar levels. For diabetic patients, especially those whose staple food is starch, acarbose is a suitable drug.
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