1.2.2 Nickel/Photocatalyst Dual Catalysis

This chapter outlines the broad scope of photoredox/nickel dual catalysis. Among the newer approaches to organic synthesis that engender the concept of dual catalysis, photoredox/nickel dual-catalytic cross-coupling reactions comprise one of the most rapidly developing and powerful tactics. Taken as a whole, these transformations enable novel carbon–carbon and carbon–heteroatom bond constructions that were previously challenging, if not impossible, to carry out. Most remarkably, these processes are most often carried out under near-neutral reaction conditions at ambient temperatures, with the energy to drive the reactions being provided solely by visible-light sources, thus enabling the incorporation of a broad range of diverse functional groups. As described, the development of these processes therefore provides one means to address the longstanding challenge of late-stage assembly of highly functionalized molecules via cross-coupling strategies.