4-甲氧基-2-硝基苯胺杂环衍生物的合成、鉴定及抗菌活性评价

Sabah Matrood Mezaal, S. Adnan
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引用次数: 1

摘要

这项研究涉及合成。新型杂环衍生物(喹唑啉和噻嗪酮)衍生物,该化合物由(4-甲氧基-2-硝基苯胺)与2,4-二甲氧基苯乙酮起始反应生成偶氮衍生物(A), (A)与芳香胺衍生物相互作用生成亚胺化合物(B1-B2),亚胺衍生物与(邻氨基苯甲酸,2-巯基苯甲酸)相互作用生成杂环衍生物喹唑啉(C1-C2)和噻嗪酮(D1-D2)。所有化合物都通过13c - nmr, FT-IR, 1hnmr进行了表征。然后,我们研究了所有杂环衍生物的生物学性质。两种不同的细菌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis , identification and evaluation of antibacterial activity for some new heterocyclic derivatives from 4-methoxy-2-nitroaniline
This research involved synthesis. novel  heterocyclic derivatives (quinazoline and thiazinone)  derivatives , this compounds prepared from starting react (4-methoxy-2-nitroaniline) with 2,4-dimethoxyacetophenone  to gate azo derivative (A) , (A) interact with aromatic amine derivatives to produce imine compounds (B1-B2), imine derivatives  interact with (anthranilic acid , 2-mercaptobenzoic) to get heterocyclic derivatives quinazoline (C1-C2) and thiazinone (D1-D2 ) . All these compound characterized by13 C-NMR , FT-IR , 1HMNR . Then that,we studies the,biological,properties for,all heterocyclic  derivatives,to,ward.two different kindof bacteria.
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