Excrétion biliaire chez le porc : niveau et réponse au repas

A technique for permanent fistulation of the bile duct, associated with a permanent fistulation of the duodenum allowing continuous reintroduction of the collected bile, was used to investigate the level and daily kinetics of biliary excretion in the conscious pig. Seven Large-White pigs of 45 kg live weight were fistulated. Volumes and total excreted bile salts were measured in hourly samples. Results show that within 24 hrs.the volume of the collected bile was about 2100 ml and the total amount of bile salts about 37 g. The bile excretion (volume and bile salts) was minimum before the morning meal (9:00 a. m.) and the total amount of the excreted bile salts immediately increased after diet intake. Within 2 hrs. after the morning and afternoon meals, values were about 300 p. 100 higher than those determined at 9:00 a. m. This increase was essentially the result of the excretion of a highly concentrated bile (200 to 300 p. 100 more than the values at 9:00 a. m.). On the other hand, the bile volumes were only affected 2 to 3 hrs. after diet intake.