悬臂式分子构型传感器研究

Qinwen Huang, Kai Li, Binbin Jiao, Tianchun Ye, Dapeng Chen, Y. Ou, Chaobo Li, Qingchuan Zhang
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引用次数: 0

摘要

微加工悬臂梁作为传感器在化学和生物传感器中越来越受欢迎。在这里,实验室原型的评估是微悬臂为基础的光学检测演示。分子吸附在悬臂梁表面时,表面应力会发生变化,这为通过测量悬臂梁的弯曲度来进行化学和生物检测提供了一种有吸引力的方法。在这项工作中,制作了不同形状的悬臂梁。通过比较不同微悬臂形状端面的反射光强度和不同微悬臂形状在液体中的稳定性,对微悬臂结构进行了初步评价。结果表明,以叶片为平镜的三角形悬臂梁具有较好的反光性能和液体稳定性。然后,利用悬臂式传感器检测PNIPAM分子随温度变化的构象变化
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cantilever-based Transducer for Molecules Configuration Research
Microfabricated cantilevers have recently become increasingly popular as transducers in chemical and biological sensors. Here, an evaluation of laboratory prototype that is microcantilever-based optical detection is demonstrated. Surface stress changes when molecules adsorb on cantilevers surface, which offers an attractive way to chemical and biological detection by measuring the bending of cantilevers. In this work, different figures of cantilevers were fabricated. Preliminary evaluation of these microfabricated cantilevers was performed by comparing the intensity of reflecting light on the end surfaces of different cantilever figures and the stability of different cantilever figures in liquid. The result demonstrated that triangle cantilever with paddle acting as a flat mirror has better performance of light reflecting and stability in liquid. Then, cantilevers-based sensors were used to detect the conformational changes in PNIPAM molecules with temperature changing
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