一种用于皮层内三维电极阵列的微组装结构

Q. Bai, K. Wise, J. Hetke, D. Anderson
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引用次数: 3

摘要

一种实用的微组装工艺已经被开发出来,以创建三维(3D)微电极阵列,用于记录和刺激中枢神经系统,使用微机械的二维探针组件。探头和皮质表面平台之间的正交导线转移是通过使用无线超声键合将探头上的金束连接到平台上的衬垫上形成的。探头的低轮廓(150 /spl mu/m)支腿设计允许连接完全组装的高密度阵列。微机械加工的微工具可以在大约30分钟内完成整个阵列组装。在200 /spl mu/m的中心上实现了高达8/spl次/16柄的阵列,并成功地用于记录皮质单单元。动态插入装置也已被探索,使这些高密度探针阵列能够高速植入猫的皮层。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A microassembly structure for intracortical three-dimensional electrode arrays
A practical microassembly process has been developed to create three-dimensional (3D) microelectrode arrays for recording and stimulation in the central nervous system using micromachined 2D probe components. Orthogonal lead transfers between the probes and a cortical surface platform are formed by attaching gold beams on the probes to pads on the platform using wire-free ultrasonic bonding. The low-profile (150 /spl mu/m) outrigger design of the probes allows the bonding of fully-assembled high-density arrays. Micromachined microtools allow full array assembly in about 30 minutes. Arrays having up to 8/spl times/16-shanks on 200 /spl mu/m centers have been realized and used to record cortical single units successfully. Dynamic insertion devices have also been explored to allow the implantation of these high-density probe arrays into feline cortex at high speed.
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