头颈癌——印度安得拉邦的患病率和危险因素:初步分析

A. Vangara, V. Rao, K. Ranganath, J. Reddy, D. Vinod
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引用次数: 0

摘要

目的:本文的目的是通过医院数据研究安得拉邦头颈癌(HNC)的患病率、危险因素、诊断阶段、部位和组织病理学状况,并与该邦其他地区的可用数据进行比较。材料与方法:对2010 - 2018年医院病历及临床档案资料进行回顾性分析。分析患者的地理区域、危险因素、分期等。分期是根据T-肿瘤大小,N -淋巴结状态,M -转移状态(TNM)分类和分组分期来完成的。根据国际肿瘤疾病分类(ICD-02)对癌症部位进行分类。结果:本研究共发现HNC患者2544例。我们注意到明显的男性优势。患者以40 ~ 60岁年龄组居多(P < 0.001)。男性和女性的危险因素或习惯是吸烟、饮酒、咀嚼或这些因素的组合(P < 0.001)。在两性中,所有的危险因素主要出现在舌、咽下和颊粘膜。口腔黏膜患者主要与嚼烟习惯有关,以男性为主。大多数早期疾病(第1和第2阶段)发生在女性身上,而晚期(第3和第4阶段)发生在男性身上。(p值< 0.001)。结论:吸烟、饮酒、咀嚼是常见的危险因素。在本研究中存在男性优势。舌癌和下咽癌与吸烟和饮酒有关,而咀嚼癌则与颊粘膜癌有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Head and neck cancers – Prevalence and risk factors in Andhra Pradesh state, India: A preliminary analysis
Aim: The aim of this article is to study the prevalence of Head and Neck Cancers (HNC), risk factors, stage at diagnosis, site, and histopathology status in Andhra Pradesh from a hospital-based data and compared with the data available in other areas in the state. Materials and Methods: A retrospective analysis is carried out from the hospital data collected from the records and clinical files from the years 2010 to 2018. Patient's geographical area, risk factors, staging, etc., are analysed. Staging is done based on T- tumour size, N – Lymph nodal status, M – metastases status (TNM) classification and group stage. The cancer site is classified based on International Classification of Disease (ICD) for oncology (ICD-02). Results: 2544 patients of HNC are found in this study. A significant male predominance is noticed. Majority of the patients belong to the 40–60 age group (P < 0.001). The risk factors or habits are smoking, alcohol, chewing or combination of these in both males and females (P < 0.001). In both the sexes all the risk factors are seen mainly in tongue, hypo pharynx, and buccal mucosa. And, buccal mucosa patients are associated mainly with chewing tobacco habit, with male predominance. Most of the early stage disease (Stages 1 and 2) are noticed in females, whereas late stages (Stages 3 and 4) are noticed in males. (p-value < 0.001). Conclusion: Smoking, alcohol, and chewing are the common risk factors found among the patients. There is male predominance in the present study. Tongue and hypo pharynx cancers are associated with smoking and alcohol whereas chewing is found in buccal mucosa cancers.
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