胚胎移植中的鞘。提高ICSI周期妊娠率的一步

A. Galal, mohamed mehesen, Ahmad Etman, M. Elmohamady
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摘要

目的:比较经典胚胎移植和鞘胚胎移植技术。研究设计:回顾性病例对照。材料和方法:在多中心生育中心进行回顾性病例对照。41,500名不孕症妇女接受了ICSI,其中3110名接受了新鲜胚胎移植,1005名接受了冷冻胚胎移植。在引入胚胎加载的内鞘之前,先对外鞘进行自信定位,而经典技术是同时引入两种导管。两组的临床妊娠率(定义为胚胎移植后6-8周出现胎心搏动)。结果:共评估3110例胚胎移植。1767例(56.8%)采用经典胚胎移植法,1343例(42.2%)采用鞘内移植法。总体妊娠率为50.8%,其中经典胚胎移植法52.5%,鞘内移植法48.6%,差异有统计学意义。无困难胚胎移植的受孕率为51%(与经典移植相当),与经典移植失败的困难病例相比,受孕率为43.3%。冷冻胚胎移植中,鞘组的受孕率明显高于经典移植组(60.6%比52.9%)。结论:鞘内胚胎移植是一种有效的技术,在非复杂病例中妊娠率相当,在困难病例中妊娠率较高,操作简单,创伤性好,易于标准化
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sheath in Embryo Transfer. A Step Towards Improving Pregnancy Rate in ICSI Cycles
Aim: To compare classic embryo transfer versus sheath in techniques of embryo transfer. Study Design: Retrospective case control. Materials and Methods: Retrospective case control that was conducted in Multicenter fertility centers. Four thousands one hundred and fifteen infertile women undergoing ICSI with 3110 underwent fresh embryo transfer and 1005 underwent frozen embryo transfer. Sheath in technique conducted by confident positioning of the outer sheath before introducing embryo loaded inner sheath while classic technique both catheters introduced simultaneously. Primary outcomes Clinical pregnancy rate (defined as the presence of pulsating fetal heart after 6-8 weeks of Embryo transfer) in both groups. Results: A total of 3110 embryo transfer were evaluated. in 1767 (56.8% ) classic embryo transfer method was used compared to 1343 (42.2% ) sheath in .The overall pregnancy rate is 50.8 % being 52.5 % within classic embryo transfer compared to 48.6 % within sheath in transfer that was statistically significant. Sheath in embryo transfer yield 51% pregnancy rate in non-difficult embryo transfer ( comparable to classic transfer ) and yield 43.3 % in difficult cases compared to failure of transfer with classic type .Pregnancy rate i8n frozen embryo transfer was significantly higher in sheath in group versus classic transfer (60.6 % versus 52.9%). Conclusion: Sheath in Embryo transfer is a valid technique yield comparable pregnancy rate in non-complicated cases and non-comparable higher pregnancy rate in difficult cases .it is simple a traumatic techniques easy to be standardized
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