不孕症患者卵巢储备功能与血型有关系吗?

Ozgur Kan, U. Gorkem, A. Alkilic, Deniz Taskiran, Ozgur Kocak, E. Yıldırım, C. Togrul
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摘要

目的:评价不孕症患者的卵巢储备能力已成为辅助生殖技术(ART)成功与否的重要概念。最近的研究报道了血型和卵巢储备之间的联系。因此,本研究的目的是分析不孕症患者血型与卵巢储备的关系。研究设计:在这项回顾性、观察性和单中心研究中,共纳入了2018年1月至2018年11月期间申请寻求生育的311名妇女。以卵泡早期血清促卵泡激素水平(>10 mLU/mL)和窦卵泡计数(≤5)作为卵巢储备阈值,反映卵巢储备减少(DOR)。主要结果是血型和卵巢储备之间的关系。次要结局是生化和临床妊娠率。结果:不同血型与促卵泡激素(FSH)水平无相关性。FSH水平升高仅与年龄和窦卵泡计数有关。与卵巢储备的结果类似,生化和临床妊娠结局不受血型和恒河因子的影响。结论:患者血型对卵巢储备功能无影响。此外,血型和恒河因子都不能预测抗逆转录病毒治疗患者的妊娠结局。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is there a relationship between ovarian reserve and blood groups in infertile patients?
Objective: Evaluation of ovarian reserve in infertile patients had become an important concept in assisted reproductive techniques (ART) success work-up. Recent studies reported an association between blood type and ovarian reserve. Therefore, the aim of this study was to analyze the relationship between blood type and ovarian reserve in infertile patients. Study Design: In this retrospective, observational and single-center study, a total of 311 women who were applied for fertility seek between January 2018 and November 2018 were included. As a threshold of ovarian reserve, - serum follicle stimulating hormone levels (>10 mLU/mL) and antral follicle counts (≤5) at early follicular phase were taken to reflect diminished ovarian reserve (DOR). The main outcome was the association between blood types and ovarian reserve. Secondary outcomes were biochemical and clinical pregnancy rates. Results: There was no relationship between blood types and follicle stimulating hormone levels (FSH). Elevated FSH levels were associated with only age and antral follicle count. Similar to the results of ovarian reserve, biochemical and clinical pregnancy outcomes are not affected by blood groups and Rhesus factor. Conclusion: Patients' blood type did not have any impact on ovarian reserve. In addition, neither blood type nor rhesus factor have an effect on predicting pregnancy outcomes in ART patients.
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