智能巧克力作为新一代功能食品的平台

I. Petyaev, V. Tsibezov, N. Kyle, N. Chalyk, V. Klochkov
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引用次数: 0

摘要

我们已经开发了一种方法,可以通过将可可黄烷醇嵌入番茄红素或其他类胡萝卜素中来保护它们。这就增加了它们在消化道中的“存活率”,从而提高了它们的吸收和功效。临床研究表明,我们的方法可以提高这些分子的生物利用度,提高它们的功效,因此一块5-10g的黑巧克力具有100g未经修饰的黑巧克力的功效。我们使用这种富含可可黄烷醇的智能巧克力作为平台,将其他具有既定生理特性的食品生物活性分子结合起来。其中包括保护血浆脂蛋白的番茄红素,支持神经元组织的叶黄素和玉米黄质,以及促进线粒体呼吸的虾青素。临床验证结果表明,其功效优于未经改性的黑巧克力和传统补充剂。此外,我们将这个平台与反式白藜芦醇结合起来。该分子在临床应用中的主要问题是其分离形式的生物利用度比与红酒一起食用时低100 - 1000。通过使用我们的技术,我们开发出了将t-RSV生物利用度提高到红酒水平的巧克力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Smart Chocolate as a Platform for New Generation of Functional Food
We have developed a process, which can protect cocoa flavanols by embedding them into lycopene, or other carotenoids. This results in an increase in their ‘survival’ in the digestive tract, and consequently in an improvement in their absorption and efficacy. Clinical studies demonstrated that our process can improve the bioavailability of these molecules and increase their efficacy so that a piece of 5-10g has the power of 100g of unmodified dark chocolate. We used this enriched cocoa flavanol Smart Chocolate as a platform to combine other food bioactive molecules with established physiological properties. They included lycopene to protect plasma lipoproteins, lutein and zeaxanthin to support neuron tissues, and astaxanthin to boost mitochondria respiration. Results of clinical validation demonstrated their superior efficacy above unmodified dark chocolate and conventional supplementation. In addition we combined this platform with trans-resveratrol. The main problem in clinical application of this molecule is that in isolated form its bioavailability 100 to 1,000 lower than when it is consumed with red wine. By using our technology we developed chocolate with bioavailability of t-RSV boosted to the level of red wine.
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