模拟微重力和不同环境温度下大鼠生理参数变化的调控规律

Jie Qian, Gengxin Xie, Jie Zheng, Bo Duan, Yajun Cao, Xi Wang, Fengjie Li, Changpeng Hu
{"title":"模拟微重力和不同环境温度下大鼠生理参数变化的调控规律","authors":"Jie Qian, Gengxin Xie, Jie Zheng, Bo Duan, Yajun Cao, Xi Wang, Fengjie Li, Changpeng Hu","doi":"10.11648/J.AJCE.20190701.15","DOIUrl":null,"url":null,"abstract":"To investigate the rules regulating changes in mean chest temperature (MCT), mean rectal temperature (MRT) and mean body weight (MW)in rats at simulated microgravity and different ambient temperatures (ATs). The −30o rat tail suspension (TS) method was used to simulate microgravity over a 7 day period at 18°C, 20°C, 23°C and 26°C AT through comparison between the TS group and control group. Each group contained six male SD rats (including one verification rat). MCT and MRT of TS group rats increased at all four levels of AT. MCT and MRT reached maximum growth rates of 0.315 and 0.118 at ATs of 20°C and 23°C, respectively. MW was reduced at ATs of 20°C and 23°C, whereas it increased at 18°C and 26°C AT in the TS group. The rates of changes of MCT, MRT and MW at different ATs were analyzed using linear regression analysis for both the control (Equation 1) and TS (Equation 2) groups. Using A new equation (Equation 3) without the influence of other factors was derived after Equation 1 minus Equation 2 to derive. The result shows that the coefficients of Equation 3 are different under the four ATs. TS and AT have coupling effects on the MCT, MRT and MW of rats.","PeriodicalId":7606,"journal":{"name":"American Journal of Civil Engineering","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rules Regulating the Change in Physiological Parameters of Rats Under Simulated Microgravity and Different Ambient Temperatures\",\"authors\":\"Jie Qian, Gengxin Xie, Jie Zheng, Bo Duan, Yajun Cao, Xi Wang, Fengjie Li, Changpeng Hu\",\"doi\":\"10.11648/J.AJCE.20190701.15\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"To investigate the rules regulating changes in mean chest temperature (MCT), mean rectal temperature (MRT) and mean body weight (MW)in rats at simulated microgravity and different ambient temperatures (ATs). The −30o rat tail suspension (TS) method was used to simulate microgravity over a 7 day period at 18°C, 20°C, 23°C and 26°C AT through comparison between the TS group and control group. Each group contained six male SD rats (including one verification rat). MCT and MRT of TS group rats increased at all four levels of AT. MCT and MRT reached maximum growth rates of 0.315 and 0.118 at ATs of 20°C and 23°C, respectively. MW was reduced at ATs of 20°C and 23°C, whereas it increased at 18°C and 26°C AT in the TS group. The rates of changes of MCT, MRT and MW at different ATs were analyzed using linear regression analysis for both the control (Equation 1) and TS (Equation 2) groups. Using A new equation (Equation 3) without the influence of other factors was derived after Equation 1 minus Equation 2 to derive. The result shows that the coefficients of Equation 3 are different under the four ATs. TS and AT have coupling effects on the MCT, MRT and MW of rats.\",\"PeriodicalId\":7606,\"journal\":{\"name\":\"American Journal of Civil Engineering\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-04-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of Civil Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.11648/J.AJCE.20190701.15\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Civil Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11648/J.AJCE.20190701.15","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

探讨模拟微重力和不同环境温度下大鼠平均胸温(MCT)、平均直肠温度(MRT)和平均体重(MW)的变化规律。采用- 300大鼠尾悬液(TS)法,在18°C、20°C、23°C和26°C at下模拟7 d的微重力,将TS组与对照组进行比较。每组6只雄性SD大鼠(其中1只验证大鼠)。TS组大鼠的MCT和MRT在四个水平at均升高。在20°C和23°C温度下,MCT和MRT的最大生长速率分别为0.315和0.118。在20°C和23°C的温度下,TS组的MW降低,而在18°C和26°C的温度下,TS组的MW增加。采用线性回归分析对照组(方程1)和TS组(方程2)不同at时MCT、MRT和MW的变化率。在方程1 -方程2的基础上推导出不受其他因素影响的新方程(方程3)。结果表明,在4种工况下,式3的系数是不同的。TS和AT对大鼠MCT、MRT和MW有耦合作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rules Regulating the Change in Physiological Parameters of Rats Under Simulated Microgravity and Different Ambient Temperatures
To investigate the rules regulating changes in mean chest temperature (MCT), mean rectal temperature (MRT) and mean body weight (MW)in rats at simulated microgravity and different ambient temperatures (ATs). The −30o rat tail suspension (TS) method was used to simulate microgravity over a 7 day period at 18°C, 20°C, 23°C and 26°C AT through comparison between the TS group and control group. Each group contained six male SD rats (including one verification rat). MCT and MRT of TS group rats increased at all four levels of AT. MCT and MRT reached maximum growth rates of 0.315 and 0.118 at ATs of 20°C and 23°C, respectively. MW was reduced at ATs of 20°C and 23°C, whereas it increased at 18°C and 26°C AT in the TS group. The rates of changes of MCT, MRT and MW at different ATs were analyzed using linear regression analysis for both the control (Equation 1) and TS (Equation 2) groups. Using A new equation (Equation 3) without the influence of other factors was derived after Equation 1 minus Equation 2 to derive. The result shows that the coefficients of Equation 3 are different under the four ATs. TS and AT have coupling effects on the MCT, MRT and MW of rats.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信