P. D. Tuan, Tran Thi Van Anh, N. Hai, Ha Quang Loi, Dao Viet Hung, Ha Thanh Hoa, N. Diep, Ngo Thi Xuan Thinh
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引用次数: 0
摘要
金银花是一种广泛使用的越南药材,是金银花(Lonicera japonica Thunb)的干芽或花。,以及其他几个忍冬属的种类,如忍冬。,金银花DC。,柬埔寨金银花(Lonicera cambodianpierre ex Danguy),属辣椒科。这种材料在传统医学中被用于清热、排毒、散风热。根据近年来各种植物化学和生物学的研究,我们系统地总结了金银花含有129种酚类衍生物,包括48种黄酮类化合物,13种木脂素和新木脂素,55种酚酸衍生物和13种其他酚类化合物。这些酚类化合物具有显著的抗菌、抗病毒、抗氧化、抗炎、抗癌、保肝、抗内毒素、抗过敏、抗糖尿病、保护心脏、抗过敏等生物学作用。其中绿原酸作为一种重要的生物活性成分,在越南药典和中国药典中被用作金银花质量评价的标志化合物。
Flos Lonicerae: A Review of Chemical Structures and Biological Activities of Phenolic Derivatives
Flos Lonicerae, a widely used Vietnamese medicinal material, is the dried buds or flowers of Lonicera japonica Thunb., and several other species of genus Lonicera such as Lonicera dasystyla Rehd., Lonicera confusa DC., Lonicera cambodiana Pierre ex Danguy, belonging to the family Caprifoliaceae. This material has been used for a long time in traditional medicine for clearing heat, removing toxins, and dispersing wind heat. According to a variety of recent phytochemistry and biological studies that we systematically summarized, Flos Lonicerae contains 129 phenolic derivatives including 48 flavonoids, 13 lignans and neolignans, 55 phenolic acid derivatives, and 13 other phenolic compounds. These phenolic compounds have remarkable biological effects such as antibacterial, antiviral, antioxidant, anti-inflammatory, anti-cancer, hepatoprotective, anti-endotoxin, anti-allergic, anti-diabetic, cardioprotective, anti-allergic activities, etc. In particular, chlorogenic acid, a prominent component with significant biological activities, is utilized as a marker compound to evaluate the quality of Flos Lonicerae in the Vietnamese and Chinese Pharmacopoeia.