致编辑的信:在增加应激环境(微重力)下观察到分泌率增加后对青霉菌分泌途径的基因编辑，迪拜高中生的研究提案

Fine focus Pub Date : 2018-12-21 DOI:10.33043/FF.4.2.163-169

A. Shirali, Wilson Minter Huijsmans, M. Sottocornola

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引用次数: 1

摘要

在这项研究中，我们的目标是利用miniPCR和/或RTQ-PCR扩增青霉菌在ISS或类似的模拟微重力下的分泌途径，然后利用CRISPR cas-9 (Clustered Regularly Interspaced Short Palindromic Repeats)优化青霉菌的功能，这是遗传学中的一项新技术，可以帮助基因改变以更好地生产药物。青霉菌的分泌途径受pcbAB、pcbC和penDE基因控制

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Letter to the Editor: Genetic Editing of Secretory Pathway of Penicillium Chrysogenum After Observation of Increased Secretory Rates in an Increased Stress Environment (Microgravity), a Research Proposal by High School Students in Dubai

In this study, we aim to amplify the secretory pathway of Penicillium Chrysogenum within the ISS or similar simulated microgravity using the miniPCR and/or RTQ-PCR and then optimizing Penicillium Chrysogenum function using CRISPR cas-9 (Clustered Regularly Interspaced Short Palindromic Repeats), a new technology in the genetics which can help in gene alteration for better drug production. The secretory pathway of Penicillium Chrysogenum is controlled by genes pcbAB , pcbC and penDE

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Fine focus

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