摩洛哥男性乳腺癌:流行病学和预后因素。约140宗个案

K. Alaoui Slimani , A. Debbagh , Y. Sbitti , H. Errihani , M. Ichou
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引用次数: 1

摘要

目的男性乳腺癌较为罕见;它占男性所有恶性肿瘤的0.2% - 1.5%,占所有乳腺癌的1%。方法回顾性分析1998年至2007年在摩洛哥拉巴特国家肿瘤研究所和军队医院收集的140例本病的流行病学、临床、治疗和发展概况。结果患者平均年龄61岁。超重的发生率很高。最常见的临床表现是坚固的乳晕下肿块,占83%。最常见的病理类型是浸润性导管癌(93%)。激素受体在86%的病例中呈阳性。85%的患者接受了单纯乳房切除术和腋窝清扫,68%的患者术后接受了胸壁照射,54%的患者接受了化疗,82%的患者接受了激素治疗。中位随访时间为91.1个月。估计5年和10年的总生存率分别为68%和74%。结论男性和女性乳腺癌的处理方法相同,分期预后相同。未来的研究需要更好地了解这种疾病,以改善男性患者的管理和预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cancer du sein chez l’homme au Maroc : épidémiologie et facteurs pronostiques. À propos de 140 cas

Objectives

Male breast cancer is rare; it constitutes 0.2–1.5 % of all malignant tumors in men and 1 % of all breast cancers.

Methods

The goal of this retrospective study is to analyze the epidemiologic, clinic, therapeutic and evolutive profiles of this disease in 140 cases collected at the National Institute of Oncology and military hospital in Rabat, Morocco, between the years 1998 and 2007.

Results

The mean age was 61 years. A high incidence of overweight was found. The most frequent clinical presentation was a firm subareolar lump in 83 % of cases. The most common pathological type was an infiltrating ductal carcinoma (93 %). Hormone receptors were positive in 86 % of cases. Eighty-five percent of patients underwent simple mastectomy and axillary dissection, 68 % chest wall irradiation after surgery, 54 % received chemotherapy and 82 % hormonal therapy. Median follow-up was 91.1 months. The estimated 5-year and 10-year overall survival was respectively 68 % and 74 %.

Conclusion

The management of male and female breast carcinoma is the same, as well as their prognosis at equal stages. Future research for better understanding of this disease are needed to improve the management and prognosis of male patients.

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