酶促生物聚合反应器的准稳态近似

R. A. M. Noor, Z. Ahmad, M. H. Uzir
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引用次数: 0

摘要

生物高聚物已成为近十年来替代材料的最新趋势之一。人们对环境问题的意识不断提高,这激发了人们创造替代材料的想法,以逐步取代现有的石油基聚合物。聚己内酯(PCL)是一种已成为商业生物聚合物的生物聚合物。这项工作的重点是动力学的生物聚合过程在反应器PCL。基于Briggs和Haldane提出的准稳态近似,推导了生物聚合过程的数学表达式。该模型是根据生物聚合反应的机理模型建立的,用于推测生物聚合物的分子量。在此基础上,基于准稳态近似方法建立的数学模型可以成功地预测分子质量。并将实验所得的实际分子量与数学模型所得的模拟分子量进行了比较。用统计方法对数学模型的预测结果进行了分析。生物高聚物已成为近十年来替代材料的最新趋势之一。人们对环境问题的意识不断提高,这激发了人们创造替代材料的想法,以逐步取代现有的石油基聚合物。聚己内酯(PCL)是一种已成为商业生物聚合物的生物聚合物。这项工作的重点是动力学的生物聚合过程在反应器PCL。基于Briggs和Haldane提出的准稳态近似,推导了生物聚合过程的数学表达式。该模型是根据生物聚合反应的机理模型建立的,用于推测生物聚合物的分子量。在此基础上,基于准稳态近似方法建立的数学模型可以成功地预测分子质量。并将实验所得的实际分子量与实验所得的模拟分子量进行了比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quasi steady state approximation in enzymatic biopolymerization reactor
Biopolymer has become one of the recent trends for alternative materials in this decade. The rising awareness towards environmental issues has sparked the idea of creating alternative materials to gradually replace the existing petroleum based polymer. Polycaprolactone (PCL) is amongst the biopolymer that has emerged to be a commercial biopolymer. This work focuses on the kinetics of the biopolymerization process in a reactor for PCL. Mathematical representation of biopolymerization process was derived based on Quasi Steady State Approximation proposed by Briggs and Haldane. The model was developed to infer the molecular weight of the biopolymer which is based on the mechanistic model of the biopolymerization reaction. Based on the results, the molecular weight can be successfully predicted by the developed mathematical model based on the Quasi Steady State Approximation method. Comparison was also carried out between actual molecular weight from experimental works and simulated molecular weight from the mathematical model. The analysis on the mathematical model predictions were conducted using statistical means was also presented in this paper.Biopolymer has become one of the recent trends for alternative materials in this decade. The rising awareness towards environmental issues has sparked the idea of creating alternative materials to gradually replace the existing petroleum based polymer. Polycaprolactone (PCL) is amongst the biopolymer that has emerged to be a commercial biopolymer. This work focuses on the kinetics of the biopolymerization process in a reactor for PCL. Mathematical representation of biopolymerization process was derived based on Quasi Steady State Approximation proposed by Briggs and Haldane. The model was developed to infer the molecular weight of the biopolymer which is based on the mechanistic model of the biopolymerization reaction. Based on the results, the molecular weight can be successfully predicted by the developed mathematical model based on the Quasi Steady State Approximation method. Comparison was also carried out between actual molecular weight from experimental works and simulated molecular weight from the ...
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