膀胱生长的光谱和表现:一项单中心回顾性研究

D. Paudel, H. Regmi, U. Bajracharya, G. K. Shrestha
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引用次数: 3

摘要

导言:膀胱癌是一种异质性疾病,由不同类型的肿瘤组成。膀胱疾病,无论是肿瘤还是非肿瘤,都有显著的死亡率和发病率。组织病理学仍然是诊断的金标准。经尿道膀胱肿瘤切除术是一种确保组织病理学诊断所需材料的治疗方法,因为它可以评估肿瘤的分化程度、浸润深度,以及对诊断和预后评估有用的参数。材料和方法:1年内所有在病理实验室提交的膀胱活检均纳入研究。结果:本组51例患者中,男女比例为4.67:1,年龄22 ~ 96岁。在研究人群中,30人(52.7%)表现为血尿,10人(19.2%)表现为排尿灼烧、尿频和下腹痛。研究中44例(86%)为肿瘤病变,其余7例(14%)为非肿瘤病变。23%(12/51)的患者诊断为浸润性尿路上皮癌,分级高低。结论:本研究显示肿瘤病变比非肿瘤病变更常见。绝大多数肿瘤病变起源于尿路上皮。其中大多数为侵袭性尿路上皮肿瘤。所有的尿路上皮肿瘤多见于男性。膀胱镜检查和活检有助于早期发现膀胱肿瘤,它们是诊断和随访的主要手段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spectrum and Presentation of Urinary Bladder Growth: a Single-Center Retrospective Study
Introduction: Urinary bladder cancers are heterogeneous diseases consisting of a divergent group of tumors.  Diseases of the urinary bladder, both neoplastic and nonneoplastic contribute to notable mortality and morbidity. Histopathology remains the gold standard of diagnosis. Bladder transurethral resection of the tumor is a therapeutic procedure that ensures the material necessary for histopathological diagnosis because it allows assessment of the degree of differentiation, depth of tumor invasion, parameters useful in the elaboration of diagnosis and prognosis assessment Material and Methods: All the urinary bladder biopsies submitted in the pathology laboratory during 1 year time period were included in the study. Results: Among the 51 total cases in the study, the male to female ratio was 4.67:1 with the age group of 22-96 years. Among the study population, 30 (52.7%)  presented with hematuria, 10 (19.2%)  with burning micturition, frequent urination, and lower abdominal pain. In the study, 44 (86%) showed neoplastic lesions while 7(14%) remaining were non-neoplastic lesions. Infiltrative urothelial carcinoma with low and high grades was diagnosed in  23% (12/51) Conclusions: This study has revealed that neoplastic lesions are more common than non-neoplastic lesions. A great majority of neoplastic lesions are of urothelial origin. Majority of which are invasive urothelial neoplasm. All urothelial neoplasms are more common in males. Cystoscopic studies and biopsies help in the early detection of bladder neoplasms and they form the mainstay of the diagnosis and follow-up.
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