纵隔灰色区淋巴瘤。

Mukesh Bhardwaj, Rajat Saha, D. Misra, V. Malhotra
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引用次数: 0

摘要

一名50岁男性,表现为咳嗽和呼吸困难。正电子发射断层扫描显示FDG(氟脱氧葡萄糖)纵隔肿块。真切活检显示纤维化间质组织有细胞浸润,包括异常淋巴样细胞和少数大细胞,细胞核混浊。免疫组化示CD20弥漫性阳性,CD30局灶性阳性,少见CD15阳性细胞。组织学图和免疫谱显示非霍奇金淋巴瘤和霍奇金淋巴瘤的重叠特征。诊断为纵隔灰色区淋巴瘤。病人经过六个周期的化疗,代谢反应完全。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mediastinal Gray Zone Lymphoma.
A 50-year-old male presented with cough and breathlessness. A positron emissoin tomography scan revealed FDG (Fluorodeoxyglucose) avid mediastinal mass. Tru-cut biopsy showed fibrotic stromal tissue with cellular infiltrate consisting of abnormal lymphoid cells and few large cells with smudged nucleus. Immunohistochemistry revealed diffuse positivity with CD20, focal positivity for CD30 and rare CD15 positive cells. Histological picture and immune profile showed overlaping features of non-Hodgkin's as well as Hodgkin's lymphoma. A diagnosis of mediastinal gray zone lymphoma was made. The patient showed a complete metabolic response to six cycles of chemotherapy.
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