量化髋发育不良的动态评估

Olivia Paserin, N. Quader, K. Mulpuri, A. Cooper, E. Schaeffer, A. Hodgson, R. Abugharbieh
{"title":"量化髋发育不良的动态评估","authors":"Olivia Paserin, N. Quader, K. Mulpuri, A. Cooper, E. Schaeffer, A. Hodgson, R. Abugharbieh","doi":"10.29007/ZH41","DOIUrl":null,"url":null,"abstract":"Although physical and ultrasound (US)-based screening for congenital deformities of the hip (developmental dysplasia of the hip, or DDH) is routinely performed in most countries, one of the most commonly performed manoeuvres done under ultrasound observation - dynamic assessment - has been shown to be relatively unreliable and is associated with significant misdiagnosis rates, on the order of 29%. Our overall research objective is to develop a quantitative method of assessing hip instability, which we hope will standardise diagnosis across different raters and health-centres, and may perhaps improve reliability of diagnosis. To quantify dynamic assessment, we propose to use the variability in femoral head coverage (FHC) measurements within multiple US scans collected during a dynamic assessment. In every US scan, we use our recently-developed automatic FHC measuring tool which leverages phase symmetry features to approximate vertical cortex of ilium and a random forest classifier to identify approximate location of the femoral head. Having estimated FHC in each scan, we estimate the change in FHC across all the US scans during a dynamic assessment and compare this change with variability of FHC found in previous studies. Our findings - in a dynamic assessment on an infant done by an orthopaedic surgeon, the femoral centre moved by up to 19% of its diameter during distraction, from 55% FHC to 74% FHC. This variability is similar to the variability of FHC in static US scans reported in previous studies, so the variability in FHC readings we found are not indicative of any subluxation or dislocation of the infant9s femoral head. Our clinician9s qualitative assessment concluded the hip to be normal and not indicative of instability. This suggests that our technique likely has sufficient resolution and repeatability to quantify differences in laxity between stable and unstable hips, although this presumption will have to be confirmed in a subsequent study with additional subjects. The long-term significance of this approach to evaluating dynamic assessments may lie in increasing early diagnostic sensitivity in order to prevent dysplasia remaining undetected prior to manifesting itself in early adulthood joint disease.","PeriodicalId":15048,"journal":{"name":"Journal of Bone and Joint Surgery-british Volume","volume":"12 1","pages":"62-62"},"PeriodicalIF":0.0000,"publicationDate":"2017-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"QUANTIFYING DYNAMIC ASSESSMENT OF DEVELOPMENTAL DYSPLASIA OF THE HIP\",\"authors\":\"Olivia Paserin, N. Quader, K. Mulpuri, A. Cooper, E. Schaeffer, A. Hodgson, R. Abugharbieh\",\"doi\":\"10.29007/ZH41\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Although physical and ultrasound (US)-based screening for congenital deformities of the hip (developmental dysplasia of the hip, or DDH) is routinely performed in most countries, one of the most commonly performed manoeuvres done under ultrasound observation - dynamic assessment - has been shown to be relatively unreliable and is associated with significant misdiagnosis rates, on the order of 29%. Our overall research objective is to develop a quantitative method of assessing hip instability, which we hope will standardise diagnosis across different raters and health-centres, and may perhaps improve reliability of diagnosis. To quantify dynamic assessment, we propose to use the variability in femoral head coverage (FHC) measurements within multiple US scans collected during a dynamic assessment. In every US scan, we use our recently-developed automatic FHC measuring tool which leverages phase symmetry features to approximate vertical cortex of ilium and a random forest classifier to identify approximate location of the femoral head. Having estimated FHC in each scan, we estimate the change in FHC across all the US scans during a dynamic assessment and compare this change with variability of FHC found in previous studies. Our findings - in a dynamic assessment on an infant done by an orthopaedic surgeon, the femoral centre moved by up to 19% of its diameter during distraction, from 55% FHC to 74% FHC. This variability is similar to the variability of FHC in static US scans reported in previous studies, so the variability in FHC readings we found are not indicative of any subluxation or dislocation of the infant9s femoral head. Our clinician9s qualitative assessment concluded the hip to be normal and not indicative of instability. This suggests that our technique likely has sufficient resolution and repeatability to quantify differences in laxity between stable and unstable hips, although this presumption will have to be confirmed in a subsequent study with additional subjects. The long-term significance of this approach to evaluating dynamic assessments may lie in increasing early diagnostic sensitivity in order to prevent dysplasia remaining undetected prior to manifesting itself in early adulthood joint disease.\",\"PeriodicalId\":15048,\"journal\":{\"name\":\"Journal of Bone and Joint Surgery-british Volume\",\"volume\":\"12 1\",\"pages\":\"62-62\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-06-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Bone and Joint Surgery-british Volume\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29007/ZH41\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Bone and Joint Surgery-british Volume","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29007/ZH41","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

摘要

尽管在大多数国家,以物理和超声(美国)为基础的先天性髋关节畸形(发育性髋关节发育不良,DDH)筛查是常规的,但在超声观察下进行的最常用的操作之一-动态评估-已被证明是相对不可靠的,并且与显著的误诊率相关,约为29%。我们的总体研究目标是开发一种评估髋关节不稳定的定量方法,我们希望这将使不同评分者和健康中心的诊断标准化,并可能提高诊断的可靠性。为了量化动态评估,我们建议在动态评估期间收集的多个US扫描中使用股骨头覆盖(FHC)测量的变异性。在每次US扫描中,我们使用我们最近开发的自动FHC测量工具,该工具利用相位对称特征来近似髂骨的垂直皮质,并使用随机森林分类器来识别股骨头的大致位置。在估计了每次扫描中的FHC后,我们在动态评估期间估计了所有美国扫描中FHC的变化,并将这种变化与先前研究中发现的FHC变异性进行了比较。我们的研究结果——在一名骨科医生对一名婴儿进行的动态评估中,在牵张期间,股骨中心移动了其直径的19%,从55% FHC到74% FHC。这种变异性与先前研究中报道的静态US扫描中FHC的变异性相似,因此我们发现的FHC读数的变异性并不表明婴儿股骨头有半脱位或脱位。我们的临床医生的定性评估认为髋关节是正常的,没有不稳定的迹象。这表明我们的技术可能有足够的分辨率和可重复性来量化稳定和不稳定髋关节松弛度的差异,尽管这一假设需要在后续的研究中得到更多受试者的证实。这种评估动态评估的方法的长期意义可能在于提高早期诊断的敏感性,以防止发育不良在成年早期关节疾病表现出来之前未被发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
QUANTIFYING DYNAMIC ASSESSMENT OF DEVELOPMENTAL DYSPLASIA OF THE HIP
Although physical and ultrasound (US)-based screening for congenital deformities of the hip (developmental dysplasia of the hip, or DDH) is routinely performed in most countries, one of the most commonly performed manoeuvres done under ultrasound observation - dynamic assessment - has been shown to be relatively unreliable and is associated with significant misdiagnosis rates, on the order of 29%. Our overall research objective is to develop a quantitative method of assessing hip instability, which we hope will standardise diagnosis across different raters and health-centres, and may perhaps improve reliability of diagnosis. To quantify dynamic assessment, we propose to use the variability in femoral head coverage (FHC) measurements within multiple US scans collected during a dynamic assessment. In every US scan, we use our recently-developed automatic FHC measuring tool which leverages phase symmetry features to approximate vertical cortex of ilium and a random forest classifier to identify approximate location of the femoral head. Having estimated FHC in each scan, we estimate the change in FHC across all the US scans during a dynamic assessment and compare this change with variability of FHC found in previous studies. Our findings - in a dynamic assessment on an infant done by an orthopaedic surgeon, the femoral centre moved by up to 19% of its diameter during distraction, from 55% FHC to 74% FHC. This variability is similar to the variability of FHC in static US scans reported in previous studies, so the variability in FHC readings we found are not indicative of any subluxation or dislocation of the infant9s femoral head. Our clinician9s qualitative assessment concluded the hip to be normal and not indicative of instability. This suggests that our technique likely has sufficient resolution and repeatability to quantify differences in laxity between stable and unstable hips, although this presumption will have to be confirmed in a subsequent study with additional subjects. The long-term significance of this approach to evaluating dynamic assessments may lie in increasing early diagnostic sensitivity in order to prevent dysplasia remaining undetected prior to manifesting itself in early adulthood joint disease.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
审稿时长
2 months
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信