聚合物-聚乙烯醇和聚六亚甲基胍盐酸盐的聚合物组合物,用于抗菌表面保护

V. Okladnikova, O. Ochirov, M. Grigor’eva, S. Stelmakh
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引用次数: 0

摘要

自2020年以来,表面消毒变得尤为重要,因此需要改进其实施方法。由浓缩溶液或可溶性片剂组成的传统消毒剂不能完全满足对表面进行抗菌保护的需要,需要反复使用。这导致了相当大的开支,在过去两年中,消毒剂的价格上涨了30-50%。在本文中,由于成膜抗菌成分对各种表面具有良好的粘附性,因此开发了具有延长作用的药剂,以降低消毒过程的成本并提高其效率。此外,这种系统还可以作为水漆涂料的添加剂,用于医疗和预防机构的小型维护。这些材料可以显著降低有害细菌种群的生长速度,并提供长期的保护。为实现该方法,研制了以聚乙烯醇和聚六亚甲基胍盐酸盐为基础的聚合物-聚合物组合物。应该指出的是,含有胍的聚合物具有高抗菌活性和低人体毒性的特点,也被广泛用作消毒剂的活性剂。聚乙烯醇是一种优良的成膜聚合物,具有良好的粘接性能,无毒,化学惰性。因此,使用这种添加剂可以显著减少有害细菌的传播,特别是在拥挤的公共场所。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Polymer-polymer composition of polyvinyl alcohol and polyhexamethylene guanidine hydrochloride for antimicrobial surface protection
Since 2020, surface disinfection has become particularly relevant thus requiring improved approaches to its implementation. Conventional disinfectants comprising concentrated solutions or soluble tablets fail to fully comply with the need for antimicrobial protection of surfaces, calling for their repetitive application. This leads to considerable expenses, with the price of disinfectants rising by 30–50% over the past two years. In this article, agents characterised by prolonged action due to film-forming antimicrobial components having good adhesion to various surfaces are developed in order to reduce the cost of the disinfection procedure and increase its efficiency. In addition, such systems can be used as additives to water paint coatings for minor maintenance of medical and preventive institutions. These materials can significantly reduce the growth rate of the harmful bacteria population, as well as provide long-term protection against it. In order to implement this approach, the polymer-polymer composition based on polyvinyl alcohol and polyhexamethylene guanidine hydrochloride was developed. It should be noted that guanidine-containing polymers are characterised by high antimicrobial activity and low human toxicity, being also widely used as active agents in disinfectants. An excellent film-forming polymer exhibiting good adhesive properties, polyvinyl alcohol is non-toxic and chemically inert. Thus, the use of such additives can significantly reduce the extension of harmful bacteria, especially in crowded public areas.
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