紫锥菊和水飞蓟籽对高脂饮食大鼠机体的影响

IF 0.8 Q2 Environmental Science
M. Lieshchova, V. Brygadyrenko
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引用次数: 12

摘要

过量脂肪和高热量摄入对人体的影响是许多经济发达国家面临的一个严重问题。添加紫锥菊碎籽对大鼠健康的影响Moench和Sylibum marianum (L.)Gaertn是在实验室实验中进行的。对照组动物的体重增加了700毫克/天,添加紫荆种子增加了1394毫克/天,而添加马里安种子只增加了155毫克/天。在高热量饮食中添加紫脓杆菌可显著降低肝脏、胸腺、脾脏、胃和大脑的相对重量。饲粮中添加苦参种子只显著降低了胸腺的相对重量。饲粮中添加紫癜引起血碱性磷酸酶活性显著升高,胆固醇含量升高,动脉粥样硬化指数急剧升高。与对照组相比,苦参种子提高了大鼠血液中碱性磷酸酶活性,降低了葡萄糖浓度和甘油三酯,显著降低了动脉粥样硬化指数,降低了c反应蛋白浓度。紫荆种子能增加血中红细胞和淋巴细胞的数量,而麻花种子能降低血中血小板的浓度。研究结果表明,在高血压和肝功能受损患者的饮食中,更广泛地使用苦参果作为膳食补充剂的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Echinacea purpurea and Silybum marianum seeds on the body of rats with an excessive fat diet
The impact of excess fat and high-calorie intake on the human body is an acute problem for many economically developed countries. Modelling the effects on the health of rats of supplementing their diet with crushed seeds of Echinacea purpurea (L.) Moench and Sylibum marianum (L.) Gaertn was carried out in a laboratory experiment. In the control group of animals, body weight increased by 700 mg/day, with the addition of E. purpurea seeds – by 1394 mg/day and with the addition of S. marianum seeds – by only 155 mg/day. A hypercaloric diet supplemented with E. purpurea caused a significant decrease in the relative weight of the liver, thymus, spleen, stomach, and brain. The supplementation with S. marianum seeds to the diet of animals significantly reduced only the relative weight of the thymus. Adding E. purpurea to the diet caused a strong increase in blood alkaline phosphatase activity, an increase in the cholesterol content, and a sharp increase in the atherogenic index. The seeds of S. marianum increased the alkaline phosphatase activity, reduced the glucose concentration, and triglycerides, significantly reduced the atherogenic index and lowered the C-reactive protein concentration in the rats’ blood when compared with the control group. The seeds of E. purpurea contributed to an increase in the erythrocyte and lymphocyte number in the blood, and the seeds of S. marianum – to a decrease in the thrombocyte concentration. The research results show the possibility of wider use of S. marianum fruits as a dietary supplement in the diet of patients with hypertension and impaired liver function.
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来源期刊
CiteScore
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