急性冠状动脉综合征年轻患者的临床、治疗和进化特征。有性别差异吗?

Ainhoa Robles-Mezcua, Víctor M. Becerra-Muñoz, Miguel A. López-Garrido, Hugo N. Orellana-Figueroa, Ana Guijarro-Contreras, Nasiba Abdeselam-Mohamed, Claudia Lozano-Aida, Francisco Temboury-Villaseca, Eduardo de Teresa-Galván, Manolo Jiménez-Navarro
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引用次数: 2

摘要

急性冠状动脉综合征在年轻人中的患病率估计在6%和10%左右。先前的研究表明,患有这种类型的事件的男性和年轻女性之间存在临床和进化上的差异。方法回顾性分析2006 - 2014年间我院收治的急性冠状动脉综合征患者,男性45岁以下,女性55岁以下。我们研究了心血管危险因素、冠状动脉疾病类型和治疗策略,以及随访期间的死亡率和事件。结果共纳入471例患者,其中男性283例,女性188例。高血压和糖尿病在女性中的发生率分别为46.8%和30.9%,高于男性(分别为30%和9.5%)。.001),而吸烟男性较多(88.7% vs. 68.1%, P <.001)和可卡因使用(11% vs. 1.1%, P <.011)。男性组接受血运重建术治疗的比例高于女性组(90.8% vs. 75%, P <.001)和出院时更好的医疗待遇。平均随访61.34±30.14个月,女性组长期死亡率较高(8.1%比2.3%,P = 0.004)。结论两组患者心血管危险因素分布、冠心病类型及治疗方法存在显著差异。妇女组的长期死亡率较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Características clínicas, terapéuticas y evolutivas de los pacientes jóvenes ingresados por síndrome coronario agudo. ¿Existen diferencias entre sexos?

Introduction

The prevalence of acute coronary syndrome in young population is estimated at around 6% and 10%. Previous studies have suggested clinical and evolutionary differences between men and young women suffering from an event of this type.

Methods

This was a retrospective study that included all male patients under 45 years of age and women under 55 years of age, who were admitted for acute coronary syndrome at our center between 2006 and 2014. We studied cardiovascular risk factors, type of coronary disease and treatment strategy, as well as mortality and events at follow-up.

Results

A total of 471 patients were included, 283 men and 188 women. High blood pressure and diabetes mellitus were more frequent among women (46.8% and 30.9%, respectively) than among men (30% and 9.5% respectively, P < .001), whereas there were more smoking men (88.7% vs. 68.1%, P < .001) and cocaine use (11% vs. 1.1%, P < .011). The men group received revascularization treatment in greater proportion than the women group (90.8% vs. 75%, P < .001) and better medical treatment at discharge. With a mean follow-up of 61.34 ± 30.14 months, long-term mortality was higher among the female group (8.1% vs. 2.3%, P = .004).

Conclusions

There were significant differences in the distribution of cardiovascular risk factors and type of coronary disease and treatment. Long-term mortality was higher among women group.

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