印度尼西亚医院儿童肺炎抗生素使用合理性评价

Fadhila Diah Suminar
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摘要

印度尼西亚是一个发展中国家,由于传染病,其中之一是肺炎,发病率和死亡率很高。本研究旨在描述抗生素的使用情况,使用Gyssens法确定抗生素使用的合理性,并确定抗生素使用的合理性与印度尼西亚一家公立医院和私立医院同时无PPRA的儿童肺炎患者的治疗结果之间的关系。本研究是一项横断面研究,从患者的医疗记录中收集回顾性数据。采用卡方法对抗菌药物合理使用与治疗结果的关系进行描述性分析。在印度尼西亚的一家医院和私立医院普遍使用的一种抗生素是氨苄青霉素。此外,通常开的抗生素是头孢曲松和头孢噻辛。公立医院抗菌药物使用中发现不合理使用抗菌药物83例(81.4%),完全使用抗菌药物75例(86.2%)。不合理III A类(病程长)多发生在两家医院。对合理性与治疗效果关系的研究结果进行卡方分析。结果显示,在印度尼西亚的一家医院中,经验性抗生素治疗的合理性显著提高了治疗效果(p=0.008)。在印度尼西亚一家私立医院进行的研究结果得到p值= 0,153。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
RATIONALITY EVALUATION OF ANTIBIOTIC USE IN PEDIATRIC PNEUMONIA AT HOSPITALS IN INDONESIA
Indonesia is a developing country that has high morbidity and mortality rates due to infectious diseases, one of which is pneumonia. This study aims to describe the use of antibiotics, to determine the rationality of antibiotic use using the Gyssens method, and to determine the relationship between the rationality of antibiotic use on the therapeutic outcomes of pediatric pneumonia patients in one of the public hospitals and private hospitals in Indonesia without PPRA at the same time. This study is a cross sectional study with retrospective data collection from the patient's medical record. The analysis was carried out descriptively and analytically with the Chi-square method to see the relationship between rational use of antibiotics and therapeutic outcomes. A single antibiotic which is generally used in one of the hospitals and private hospitals in Indonesia is Ampicillin. In addition, antibiotics that are often prescribed are Ceftriaxone and Cefotaxim). The use of antibiotics in Public Hospitals found 83 irrational use of antibiotics (81,4%) and 75 total uses of antibiotics (86,2%) in Private Hospitals. Irrational category III A (long duration) mostly occurs in two hospitals. The results of the research on the relationship between rationality and therapeutic outcome were analyzed by Chi-square. The results showed that the rationality of empirical antibiotic therapy significantly improved therapeutic outcomes (p=0.008) in one of the hospitals in Indonesia. The results of research conducted in one of the Indonesian private hospitals obtained p value = 0,153.
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