{"title":"高压均质工艺增强黑檀抗炎活性","authors":"H. Lee","doi":"10.12783/issn.1544-8053/14/1/23","DOIUrl":null,"url":null,"abstract":"It was first confirmed that the increase of anti-inflammatory activities of Aronia melanocarpa from high-pressure homogenization at 25,000 psi and 25°C was caused by the three times higher extraction of very heat-labile cyanidin-3-O-galactoside (C3G), a bioactive anthocyanin existing in A. melanocarpa, than that of conventional 70% ethanol extraction at 80°C. The extracts from this process showed better efficacies in suppressing the production of both nitric oxide and the cytokines, IL-6 and TNF-α, and resulted in high liver weight gain in mice. This result could be employed to extract other heat-sensitive components from various bioresources.","PeriodicalId":17101,"journal":{"name":"Journal of Residuals Science & Technology","volume":"18 1","pages":"185-192"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enhancement of Anti-inflammatory Activities of Aronia melanocarpa through High-pressure Homogenization Process\",\"authors\":\"H. Lee\",\"doi\":\"10.12783/issn.1544-8053/14/1/23\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"It was first confirmed that the increase of anti-inflammatory activities of Aronia melanocarpa from high-pressure homogenization at 25,000 psi and 25°C was caused by the three times higher extraction of very heat-labile cyanidin-3-O-galactoside (C3G), a bioactive anthocyanin existing in A. melanocarpa, than that of conventional 70% ethanol extraction at 80°C. The extracts from this process showed better efficacies in suppressing the production of both nitric oxide and the cytokines, IL-6 and TNF-α, and resulted in high liver weight gain in mice. This result could be employed to extract other heat-sensitive components from various bioresources.\",\"PeriodicalId\":17101,\"journal\":{\"name\":\"Journal of Residuals Science & Technology\",\"volume\":\"18 1\",\"pages\":\"185-192\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Residuals Science & Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.12783/issn.1544-8053/14/1/23\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Residuals Science & Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12783/issn.1544-8053/14/1/23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
首先证实,在25000 psi和25°C高压均质条件下,黑果野莓抗炎活性的增强是由于在80°C条件下提取的非常热不稳定的花青素-3- o -半乳糖苷(C3G)比传统的70%乙醇提取高3倍。该工艺的提取物对一氧化氮和细胞因子IL-6、TNF-α的产生均有较好的抑制作用,并导致小鼠肝脏增重。该结果可用于从各种生物资源中提取其他热敏成分。
Enhancement of Anti-inflammatory Activities of Aronia melanocarpa through High-pressure Homogenization Process
It was first confirmed that the increase of anti-inflammatory activities of Aronia melanocarpa from high-pressure homogenization at 25,000 psi and 25°C was caused by the three times higher extraction of very heat-labile cyanidin-3-O-galactoside (C3G), a bioactive anthocyanin existing in A. melanocarpa, than that of conventional 70% ethanol extraction at 80°C. The extracts from this process showed better efficacies in suppressing the production of both nitric oxide and the cytokines, IL-6 and TNF-α, and resulted in high liver weight gain in mice. This result could be employed to extract other heat-sensitive components from various bioresources.
期刊介绍:
The international Journal of Residuals Science & Technology (JRST) is a blind-refereed quarterly devoted to conscientious analysis and commentary regarding significant environmental sciences-oriented research and technical management of residuals in the environment. The journal provides a forum for scientific investigations addressing contamination within environmental media of air, water, soil, and biota and also offers studies exploring source, fate, transport, and ecological effects of environmental contamination.