肝癌液体活检中外泌体来源非编码rna的研究进展

Fang Zhang
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引用次数: 0

摘要

外泌体含有丰富的非编码rna,其主要功能是调控基因表达,在肝癌的发生发展中起关键作用。外泌体非编码rna有望成为肝细胞癌新的活检标志物,为肝细胞癌的早期诊断和早期治疗提供新的手段。虽然目前外泌体非编码rna的临床应用还不足,但随着研究的深入,外泌体非编码rna将在肝细胞癌的诊断、个体化治疗和预后评价中发挥越来越重要的作用。关键词:肝脏肿瘤;液体活检;液;非编码RNA
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Research progress on exosome-derived non-coding RNAs in liquid biopsy of hepatocelluar carcinoma
Exosomes contain ample non-coding RNAs, which mainly function as regulating gene expre-ssion and play key roles in the occurrence and development of hepatocellular carcinoma. Exosomal non-coding RNAs are expected to become a new biopsy marker for hepatocellular carcinoma, providing a new means for early diagnosis and early treatment of hepatocellular carcinoma.Although the clinical application of exosomal non-coding RNAs is still insufficient at present, exosomal non-coding RNAs will play an increasingly important role in the diagnosis, personalized treatment and prognosis evaluation of hepatocellular carcinoma with the deepening of research. Key words: Liver neoplasms; Liquid biopsy; Exosomes; Non-coding RNA
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