我们能预测结直肠癌吗?

A. Chandio
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引用次数: 0

摘要

背景:结直肠癌是世界范围内常见且致命的癌症,在英国,它是癌症死亡的第二大常见原因。5%的英国人一生中有患结直肠癌的风险。30%的结直肠癌患者存在转移性疾病。检测结直肠癌具有挑战性,患者可能表现为轻微症状或无症状。当病人出现症状时,癌症可能已经很晚期了。因此,建议处于平均风险的人群进行结直肠癌筛查。方法:回顾性分析2015年1月至2019年12月在英国卢顿和邓斯特布尔大学医院诊断为结直肠癌的所有患者,这些患者来自结直肠科结直肠专科护士创建的转诊数据库。通过详细审查医院病例记录,ICE/Evolve(调查和通信计算机数据库)检索数据,包括内窥镜检查;射线成像;手术过程及肿瘤随访。结果:研究期间确诊结直肠癌976例,男性513例,占52.6%,女性463例,占47.4%。平均年龄74.14岁(25 ~ 101岁)。66例6.76%的患者被排除在研究之外,因此研究参与者的百分比为男性53%(482)和女性47%(428),比例为1:1 .12。年轻人结直肠癌的发病率较低,39岁以下的发病率为1.75%(16),50岁以上的发病率为94.61%,70岁以上的发病率为60.43%。结论:提高对结直肠癌症状体征的认识是有益的。建立综合护理途径,集中复杂程序和比较国际癌症结局。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Can we predict colorectal cancer?
Background: Colorectal cancer is a common and lethal cancer worldwide, In the UK, it is the second most common cause of cancer death. 5% of UK population is at risk of colorectal carcinoma during lifetime. 30% of patients with colorectal cancer present with a metastatic disease. Detecting colorectal cancer is challenging patients may present with slight symptoms or asymptomatic. By the time patients becomes symptomatic, the cancer may be more advanced. Therefore, screening for colorectal cancer is recommended for people at average risk. Method: All patients diagnosed with colorectal cancer at the Luton and Dunstable University Hospital UK from January 2015 through December 2019 were retrospectively identified from the referral database created by colorectal specialist nurses in the colorectal service. Data were retrieved by detailed review of the hospital case notes, ICE/Evolve (Computer database for investigations and correspondence) including endoscopy; radiographic imaging; operative course and cancer follow up. Results: In the study period 976 patients were diagnosed with colorectal cancer, Male 52.6% (513) Female 47.4% (463). The mean age of 74.14 years (range, 25 to 101). Sixty six 6.76% patients were excluded from the study, therefore the percentages of studied participant were Male 53 % (482) and Female 47 % (428) ratio 1: 1.12. Incidence of colorectal cancer among young adult was low 1.75% (16) up to 39 years of age) and 94.61% are diagnosed in people over the age of 50 years, 60.43% are diagnosed in people aged 70 or over. Conclusion: Increasing awareness of the symptoms and signs of colorectal cancer be helpful and beneficial. Establish integrated care pathways, centralization of complex procedures and comparison of international cancer outcomes.
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